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| ID | Type | Description | Link |
|---|---|---|---|
| KMUHIRB-F(II)-20260160 | Other Identifier | IRB of KMUH |
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This study examines whether simple speech tasks and a swallowing screening test can help identify swallowing risk in adults of different ages. Participants will complete basic questions, a swallowing self-assessment, a saliva swallowing test, and short voice recordings of rapid syllables. The study is non-invasive, takes about 75 minutes, and may help develop an easy, low-cost screening tool for early swallowing problems.
This is a cross-sectional observational study examining the relationship between diadochokinetic (DDK) speech performance and swallowing function in community-dwelling adults aged 18 years and older. Participants will complete a single study visit, during which demographic and health-related information will be collected, the EAT-10 swallowing self-assessment will be administered, the Repetitive Saliva Swallowing Test (RSST) will be performed, and short DDK speech recordings of /pa/, /ta/, and /ka/ will be obtained in a quiet setting. Acoustic features will be extracted from the recordings and analyzed together with RSST and EAT-10 results to explore age-related differences and to develop a predictive screening model for swallowing risk. All data will be de-identified, securely stored, and retained according to study requirements.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Age-Based Cohort | Community-dwelling adults aged 18 years and older who complete a single study visit including demographic questionnaire, EAT-10, RSST, and DDK speech recordings. This is an observational cohort with no intervention, and data will be analyzed by age group. |
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| Measure | Description | Time Frame |
|---|---|---|
| Repetitive Saliva Swallowing Test Classification | Classification of swallowing function based on the Repetitive Saliva Swallowing Test (RSST). Participants will be classified as having normal RSST performance if they complete greater than or equal to 3 swallows in 30 seconds, and abnormal RSST performance if they complete fewer than 3 swallows in 30 seconds. | Day 1 |
| Measure | Description | Time Frame |
|---|---|---|
| Eating Assessment Tool-10 Total Score | Total score on the Eating Assessment Tool-10 (EAT-10), a 10-item self-report questionnaire used to assess swallowing-related symptoms. The total score ranges from 0 to 40, where higher scores indicate worse swallowing-related symptoms. A score of 3 or higher suggests possible swallowing difficulty. | Day 1 |
| Measure | Description | Time Frame |
|---|---|---|
| Participant Age | Age of participants collected at baseline, reported in years. | Day 1 |
| Participant Sex | Sex of participants collected on Day 1, reported as male or female according to the study case report form. |
Inclusion Criteria:
Exclusion Criteria:
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The study population consists of community-dwelling adults aged 18 years and older, with no upper age limit, who are able to communicate in Mandarin or Taiwanese, provide informed consent, and complete DDK tasks, RSST, and EAT-10 assessment. Participants will be recruited from community organizations and related settings in the Kaohsiung-Pingtung region. The study uses a single-visit observational design with age-based subgroup analyses and no intervention.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| HUNG C F Kaohsiung Medical University, MASTER | Contact | +8867-3121101 | #2646 #614 | gabino00076@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| GUO L Y Professor and Dean of the College of Health Sciences, Departme, Ph. D. | Department of Sports Science, Kaohsiung Medical University, Taiwan | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Sports Medicine, Kaohsiung Medical University, Taiwan | Kaohsiung City | Taiwan | 807 | Taiwan |
De-identified individual participant data collected during the trial, including baseline characteristics, intervention-related measures, and outcome data, will be shared with a data dictionary.
De-identified individual participant data (IPD) and supporting information will be available starting 2 years after publication of the primary study results and will remain accessible for 5 years.
De-identified individual participant data and related supporting documents will be made available only to qualified researchers affiliated with academic institutions, medical organizations, or public health agencies. Requesters must submit a detailed research proposal and evidence of ethical approval. Access will be granted subject to approval by the study team.
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| ID | Term |
|---|---|
| D003680 | Deglutition Disorders |
| ID | Term |
|---|---|
| D004935 | Esophageal Diseases |
| D005767 | Gastrointestinal Diseases |
| D004066 | Digestive System Diseases |
| D010608 | Pharyngeal Diseases |
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| Diadochokinetic Speech Rate | Rate of repeated diadochokinetic speech productions of /pa/, /ta/, and /ka/. The rate will be reported as syllables per second. | Day 1 |
| Diadochokinetic Speech Fundamental Frequency | Fundamental frequency (F0) extracted from repeated diadochokinetic (DDK) speech recordings of /pa/, /ta/, and /ka/. Fundamental frequency will be reported in Hertz (Hz). | Day 1 |
| Diadochokinetic Speech First Formant Frequency | First formant frequency (F1) extracted from repeated diadochokinetic (DDK) speech recordings of /pa/, /ta/, and /ka/. F1 reflects the first resonance frequency of the vocal tract and will be reported in Hertz (Hz). | Day 1 |
| Diadochokinetic Speech Second Formant Frequency | Second formant frequency (F2) extracted from repeated diadochokinetic (DDK) speech recordings of /pa/, /ta/, and /ka/. F2 reflects the second resonance frequency of the vocal tract and will be reported in Hertz (Hz). | Day 1 |
| Diadochokinetic Speech Jitter | Jitter extracted from repeated diadochokinetic (DDK) speech recordings of /pa/, /ta/, and /ka/. Jitter reflects short-term cycle-to-cycle variability in fundamental frequency and will be reported as a percentage. | Day 1 |
| Diadochokinetic Speech Shimmer | Shimmer extracted from repeated diadochokinetic (DDK) speech recordings of /pa/, /ta/, and /ka/. Shimmer reflects short-term variability in voice amplitude and will be reported in decibels (dB). | Day 1 |
| Diadochokinetic Speech Harmonics-to-Noise Ratio | Harmonics-to-noise ratio (HNR) extracted from repeated diadochokinetic (DDK) speech recordings of /pa/, /ta/, and /ka/. HNR reflects the ratio of periodic harmonic energy to noise energy in the voice signal and will be reported in decibels (dB). | Day 1 |
| Diadochokinetic Speech Root Mean Square Amplitude | Root mean square (RMS) amplitude extracted from repeated diadochokinetic (DDK) speech recordings of /pa/, /ta/, and /ka/. RMS amplitude reflects the average acoustic energy of the speech signal and will be reported in normalized amplitude units. | Day 1 |
| Diadochokinetic Speech Zero-Crossing Rate | Zero-crossing rate (ZCR) extracted from repeated diadochokinetic (DDK) speech recordings of /pa/, /ta/, and /ka/. ZCR reflects the rate at which the speech signal changes sign over time and will be reported as the number of zero crossings per second. | Day 1 |
| Day 1 |
| Education Level | Highest level of education completed by participants collected at baseline, categorized as primary school or below, junior high school, senior high school, or college or above. | Day 1 |
| Body Mass Index | Body mass index (BMI) calculated from measured height and weight at baseline. Height will be measured in meters and weight in kilograms; BMI will be reported in kg/m². | Day 1 |
| Dentition Status | Dentition status of participants collected at day 1, categorized as natural dentition, partial denture, full denture, or other. | Day 1 |
| Dry Mouth Frequency | Self-reported frequency of dry mouth symptoms collected at day 1, categorized as never, occasionally, frequently, or always. | Day 1 |
| Smoking History | Self-reported smoking history collected at baseline, categorized as never smoker, former smoker, or current smoker. | Day 1 |
| Medical History | Self-reported medical history collected at day 1 and categorized as none, hypertension, hyperglycemia, hyperlipidemia, or gastrointestinal disease (such as gastroesophageal reflux disease). | Day 1 |
| D010038 | Otorhinolaryngologic Diseases |