Effect of Bioactive Restorative Materials on Secondary Caries Prevention

Effect of Bioactive Restorative Materials on Secondary Caries Prevention: A 24-month Randomized Clinical Trial

This manuscript presents a 24-month randomised clinical trial evaluating the effectiveness of bioactive restorative materials in preventing secondary caries compared with conventional composite restorations. Four restorative materials were tested in 120 class I and II cavities among high-caries-risk adults: conventional composite (Filtek Z350 XT), glass ionomer cement (Fuji IX GP), giomer (Beautifil II), and Cention N.

Inclusion Criteria:

• Adults aged 18-55 years
• Presence of at least one primary Class I or Class II cavity in a permanent posterior tooth
• High caries risk with DMFT score ≥ 4 according to the Cariogram assessment
• Presence of at least 20 functional teeth
• Good general health
• Ability and willingness to attend follow-up and recall visits

Exclusion Criteria:

• Pregnant women
• Patients undergoing current orthodontic treatment
• Presence of severe periodontitis
• Xerostomia
• Known allergy to any restorative material component used in the study
• Bruxism or parafunctional habits