This cross-sectional analytical study aims to assess the impact of health anxiety on quality of life (QoL) among medical students at the Faculty of Medicine, Sohag University, Egypt. Health anxiety will be measured using the Short Health Anxiety Inventory (SHAI), and quality of life will be assessed using the Short Form-12 Health Survey (SF-12), covering both Physical Component Summary (PCS) and Mental Component Summary (MCS). The study targets third-year (pre-clinical) and fifth-year (clinical) students selected by cluster sampling. Findings will help identify prevalence and determinants of health anxiety and its impact on QoL, informing mental health support strategies for medical students in Upper Egypt.

A self-administered questionnaire will be used, comprising three tools: a sociodemographic data sheet, the SHAI (18 items, score 0-54), and the SF-12. Cluster sampling will be applied across student sections in the two academic years. Data will be analyzed using SPSS, including descriptive statistics, chi-square tests, correlation analysis, and multiple linear regression to identify independent predictors of QoL domains.

Inclusion Criteria:

• Medical students currently enrolled at Sohag University Faculty of Medicine
• Both genders
• provide informed consent

Exclusion Criteria:

• Students who diagnosed with severe psychiatric disorders
• Students currently receiving psychiatric treatment that may affect anxiety levels
• Incomplete questionnaires
• Students who refuse to participate

The study will be conducted among medical students in the third (final preclinical year) and fifth (final clinical year) academic years enrolled during the study period