Sleep Architecture as a Digital Biomarker for Postpartum Depression in Hong Kong Mothers

Sleep Architecture as a Digital Biomarker for Postpartum Depression in Hong Kong Mothers

The goal of this study is to develop a postpartum depression (PND) Risk index using the UK Biobank dataset, and to validate the risk index in Hong Kong postpartum women.

Participating Hong Kong postpartum women will wear an actigraphy (GENEActive) for 14 consecutive days.

Inclusion Criteria

• Mothers who are at least 18 years of age and are within 6 months of giving birth.
• Participants must be capable of reading Traditional Chinese, Mandarin, or English, to ensure they can provide informed consent and complete the required study documentation.

Exclusion Criteria

• Individuals with specific conditions that might interfere with the measurement of sleep patterns related to mood will be excluded. This includes mothers diagnosed with sleep apnea or those who use CPAP machines.
• To reduce physiological noise in the data, women working permanent night shifts or those with severe medical complications, such as pre-eclampsia requiring ongoing medication, will also be excluded