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The goal of this study is to develop a postpartum depression (PND) Risk index using the UK Biobank dataset, and to validate the risk index in Hong Kong postpartum women.
Participating Hong Kong postpartum women will wear an actigraphy (GENEActive) for 14 consecutive days.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Postpartum women |
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| Measure | Description | Time Frame |
|---|---|---|
| Postpartum depressive symptoms (PND) | PND refers to a mood disorder that affects individuals during pregnancy or within 1 year after childbirth. PND will be measured by the Edinburgh Postnatal Depression Scale (EPDS). The EPDS score ranges between 0 and 30, with higher score indicating worse PND symptoms. | 2 weeks and 6 weeks postpartum |
| Subjective sleep quality | Subjective sleep quality will be measured both subjectively by the Pittsburgh Sleep Quality Index (PSQI). The PSQI score ranges between 0 and 21, with a higher score indicating worse subjective sleep quality. | The PSQI will be reported once at 6 weeks postpartum. |
| Objective sleep efficiency | Objective sleep efficiency (SE) will be measured by the accelerometer (GENEActiv). The unit for SE is percentage, and the mathematical bounds are 0% (minimum) to 100% (maximum). However, in human populations, healthy adults typically score between 85% and 90%. A higher percentage indicates a higher SE. | Objective SE will be measured at 6 weeks postpartum for 14 consecutive days. |
| Measure | Description | Time Frame |
|---|---|---|
| Anxiety | Anxiety will be measured by the State-Trait Anxiety Inventory (STAI). The STAI score ranges between 20 and 80, with higher scores indicate more severe anxiety symptoms. | The STAI scale will be reported at 6 weeks postpartum |
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Inclusion Criteria
Exclusion Criteria
Only female will be eligible to participate this study.
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Postpartum mothers who gave birth within 6 months and reside in Hong Kong
To comply with the IRB for this study, the data will not be shared with other researchers. All collected data will be stored securely for 5 years following study completion, in accordance with institutional research data management policies. Access to the Qualtrics survey responses will be strictly limited to the principal investigator, co-investigators and research assistants. Data will be stored in password-protected files on encrypted servers, and all identifying information will be removed during data analysis and reporting. After the 5-year retention period, all data will be permanently deleted by overriding each file.
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| Type | Includes Protocol | Includes SAP | Includes ICF | Document Label | Document Date | Document Uploaded Date | Document File Name |
|---|---|---|---|---|---|---|---|
| Prot | Yes | No | No | Study Protocol | May 13, 2026 | May 13, 2026 | Prot_000.pdf |
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