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The goal of this study is to learn if a toothpaste alone and together with mouthwash works to alleviate teeth hypersensitivity in adults. It will also learn about the safety of the product.
The main question it aims to answer is:
• Does the toothpaste help to improve signs of teeth hypersensitivity? Researchers will compare sensitive teeth toothpaste and use of sensitive teeth and mouthwash to a regular toothpaste to see if it works to improve teeth sensitivity.
Participants will:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Desensitizing toothpaste | Experimental |
| |
| Desensitizing toothpaste with mouthwash | Experimental |
| |
| Regular toothpaste | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Desensitizing toothpaste | Other | Toothpaste was used two times a day (after meals) during 14 days |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change from Baseline in dentine sensitivity comparing desensitizing toothpaste versus active comparator at 14 days | From enrollment to the end of use at 14 days |
| Measure | Description | Time Frame |
|---|---|---|
| Change in dentine sensitivity from baseline in dentine sensitivity comparing desensitizing toothpaste group versus desensitizing toothpaste and mouthwash group at day 14. | From baseline to day 14 | |
| Change from baseline in pH at 14 days | From baseline to day 14 |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hospital Odontológico Universidad de Barcelona - Bellvitge | Barcelona | Spain |
Only summary of the results to support the publication will be shared. No complete study documents will be shared.
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| Type | Includes Protocol | Includes SAP | Includes ICF | Document Label | Document Date | Document Uploaded Date | Document File Name |
|---|---|---|---|---|---|---|---|
| Prot | Yes | No | No | Study Protocol | Nov 4, 2024 | May 11, 2026 | Prot_000.pdf |
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| ID | Term |
|---|---|
| D009067 | Mouthwashes |
| ID | Term |
|---|---|
| D001697 | Biomedical and Dental Materials |
| D020313 | Specialty Uses of Chemicals |
| D020164 | Chemical Actions and Uses |
| D003358 | Cosmetics |
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| Desensitizing toothpaste with mouthwash | Other | Toothpaste and mouthwash were used two times a day (after meals) during 14 days |
|
| Active comparator | Other | Toothpaste was used two times a day (after meals) during 14 days |
|
| D008420 | Manufactured Materials |
| D013676 | Technology, Industry, and Agriculture |