Acupuncture Treament in Children With Tic Disorders

Efficacy and Safety of Acupuncture in the Treatment of Tic Disorders in Children, Based on MR-DTI

This study intends to evaluate the efficacy of acupuncture on tic disorders in Children; and to explore the underlying mechanism of acupuncture intervention on tic disorders based on Magnetic Resonance Diffusion Tensor Imaging(MR-DTI).

Inclusion Criteria:

• Must meet the diagnostic criteria for Provisional Tic Disorder (PTD) or Persistent (Chronic) Motor or Vocal Tic Disorder (CTD)
• Right-handed children aged 5-18 years
• Have not previously received systematic acupuncture treatment and are able to adhere to acupuncture treatment for ≥ 2 months
• Complete medical records available
• Not currently participating in any other clinical study
• Voluntary participants, with the signature and consent of their guardians, and children aged 8 and above obtaining their own informed consent

Exclusion Criteria:

• History of hepatolenticular degeneration (Wilson's disease), rheumatic chorea, childhood migraine, epilepsy, intellectual disability, schizophrenia, or other related conditions
• Presence of organic neurological diseases or other severe conditions significantly impacting quality of life
• Recent use of centrally-acting medications
• Inability to regularly complete the acupuncture treatment regimen
• Inability to undergo the MR-DTI examination
• Refusal to sign the written informed consent form
• Inability of the child or guardian to cooperate during the treatment and follow-up process