This study evaluates an ultrasound device designed to reduce pain by targeting peripheral nerves without surgery or medication. The device is placed on the skin over the area of pain and delivers controlled ultrasound stimulation.

Adults with nerve-related pain will participate in a single study visit that includes stimulation sessions and pain assessments.

The goal of this study is to determine whether non-invasive ultrasound can safely and effectively reduce pain and to assess whether this approach is practical for future clinical use.

Inclusion Criteria:

1. Stated willingness to comply with all study procedures and availability for the duration of the study
2. Persons aged 18 and older.
3. In good general health as evidenced by medical history
4. Chronic pain located in the distribution of any of the target nerves of interest, including the occipital, suprascapular, median, femoral/leg, stellate ganglion/vagus nerves, neuroma, or amputees.

Exclusion Criteria:

• Patients with compromised skin integrity for whom device placement would result in increased risk of harm (such as those with extensive burns, active dermatologic conditions, or wounds that would prevent safe device placement)
• Pregnant patients, as the devices have not been validated in this population
• Additionally, the treating clinician may exclude any patient if they determine that study participation would be inappropriate for the patient's clinical condition.

Individual participant data (IPD) will not be shared at this stage due to the early feasibility nature of the study and the small sample size, which may increase the risk of participant re-identification. De-identified, aggregated results will be reported in publications and presentations.