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| ID | Type | Description | Link |
|---|---|---|---|
| LP-NOSE | Other Identifier | ISTANBUL TRH |
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This study investigates smell and taste function in patients diagnosed with lichen planus, a chronic inflammatory condition affecting the skin and mucous membranes.
Adults aged 18-65 with lichen planus participated in taste and smell tests. Oral and nasal examinations were performed to check for mucosal involvement, and nasal endoscopy was used to further evaluate nasal involvement.
A healthy control group of similar age also underwent taste and smell tests to compare results with the lichen planus patients.
The study aims to better understand how lichen planus affects smell and taste, which may help improve patient care. Participation is voluntary, and all information collected will be kept confidential.
The study aims to evaluate the impact of lichen planus on olfactory and gustatory functions in adults aged 18-65. Participants with lichen planus underwent taste and smell testing, oral and nasal mucosal examinations, and nasal endoscopy to detect potential mucosal involvement. A matched healthy control group also completed taste and smell tests to provide comparative data. This design allows the assessment of whether mucosal involvement in lichen planus correlates with changes in taste and smell, which may contribute to better clinical understanding and management of the disease.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group 1- Lichen Planus Patients | Participants undergo taste and smell testing, oral and nasal examinations, and nasal endoscopy to assess mucosal involvement. |
| |
| Group 2 - Healthy Controls | Participants undergo taste and smell testing to provide comparative data with the lichen planus group. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Grup 1 - Lichen Planus Patients Intervention Name: Taste and Smell Testing, Oral and Nasal Examination, Nasal Endoscopy Intervention Description: Participants undergo taste and smell testing to assess | Other | Group 1 - Lichen Planus Patients: Participants undergo taste and smell testing to assess sensory function, oral and nasal examinations to evaluate mucosal involvement, and nasal endoscopy for detailed nasal assessment. Group 2 - Healthy Controls: Participants undergo taste and smell testing to provide comparative data for the lichen planus group. |
| Measure | Description | Time Frame |
|---|---|---|
| Smell and Taste Function | Participants underwent standardized smell (olfactory) and taste (gustatory) tests to assess sensory function. Tests were performed on both lichen planus patients and healthy controls to compare results and evaluate the impact of mucosal involvement on smell and taste function. Time Frame: Single visit assessment | Day 1 |
| Smell and taste function in patients with lichen planus | Participants underwent standardized smell (olfactory) and taste (gustatory) tests to assess sensory function. Tests were performed on both lichen planus patients and healthy controls to compare results and evaluate the impact of mucosal involvement on smell and taste function. | Day 1 |
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Inclusion Criteria:
Age 18-65 years Clinically diagnosed with lichen planus (patient group) Healthy individuals without lichen planus (control group) Willing and able to provide informed consent
Exclusion Criteria:
Nasal septum deviation Nasal polyposis, congenital olfactory dysfunction, chronic rhinosinusitis, or allergic rhinitis History of head trauma History of nasal or paranasal surgery Psychiatric or neurological disorders (e.g., Parkinson's disease, Alzheimer's disease) Persistent loss of smell following COVID-19 infection Pregnancy or breastfeeding
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The study includes adults aged 18-65 years with a clinical diagnosis of lichen planus, as well as healthy volunteers without lichen planus. Participants were assessed for smell and taste function, and the patient group also underwent oral and nasal mucosal examinations, including nasal endoscopy. Both male and female participants were included.
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| Name | Affiliation | Role |
|---|---|---|
| Yasemin Bolat Eren, MD | S.B.U. Istanbul Eğitim ve Araştırma Hastanesi, Dermatology Department | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| S.B.U. Istanbul Training and Research Hospital | Istanbul | Istanbul | 34098 | Turkey (Türkiye) |
Individual participant data (IPD) will not be shared due to privacy and confidentiality considerations for study participants.
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|
| ID | Term |
|---|---|
| D008010 | Lichen Planus |
| ID | Term |
|---|---|
| D017512 | Lichenoid Eruptions |
| D017444 | Skin Diseases, Papulosquamous |
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
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