A registry for the study of the epidemiology, clinical course, and progression of myelodysplastic neoplasms (MDS), myelodysplastic/myeloproliferative neoplasms (MDS/MPN overlap syndromes), and their precursor syndromes (CHIP, CCUS)

Inclusion Criteria:

• Diagnosis of myelodysplastic syndrome (MDS), MDS/MPN overlap syndrome or evidence of myelodysplastic precursor syndrome, defined as clonal haematopoiesis without cytopenia (clonal haematopoiesis of indeterminate potential, CHIP) or clonal haematopoiesis with cytopenia (clonal cytopenia of undetermined significance, CCUS) in accordance with current WHO criteria
• Age ≥18 years
• Submission of a signed consent form for participation in the MDS Registry

Exclusion Criteria:

• No exclusion criteria have been established with regard to the registry's primary objective. In particular, patients with comorbidities and those receiving non-curative treatment may be explicitly included in order to provide a realistic picture of actual care practices
• Inclusion in the registry is excluded in cases where a written consent form is not available or where patients are unable to understand the nature and implications of participating in this registry

Diagnosis of myelodysplastic syndrome (MDS), MDS/MPN overlap syndrome, or evidence of a myelodysplastic precursor syndrome, defined as clonal hematopoiesis without cytopenia (clonal hematopoiesis of indeterminate potential, CHIP) or clonal hematopoiesis with cytopenia (clonal cytopenia of undetermined significance, CCUS) according to current WHO criteria