Effects of Sleep Quality on Functional and Cognitive Outcomes in Multiple Sclerosis

Effects of Sleep Quality on Cognitive Flexibility, Physical Activity, Body Awareness, and Reaction Time in Multiple Sclerosis

The goal of this observational study is to investigate the effects of sleep quality on cognitive flexibility, physical activity level, body awareness, and reaction time in individuals with Multiple Sclerosis.

The main question it aims to answer is:

Does sleep quality influence cognitive flexibility, physical activity level, body awareness, and reaction time in individuals with Multiple Sclerosis?

Researchers will compare individuals with good and poor sleep quality to determine whether differences in sleep quality result in variations in cognitive and physical performance outcomes.

Participants will complete standardized assessments of sleep quality, cognitive flexibility, physical activity, and body awareness, and will perform a computer-based reaction time test. In addition, participants will wear a wearable activity tracker for 7 days to objectively measure physical activity levels.

Inclusion Criteria:

• Age between 18 and 65 years
• Diagnosis of Multiple Sclerosis
• Montreal Cognitive Assessment (MoCA) score ≥24
• Expanded Disability Status Scale (EDSS) score between 0 and 6.5
• No relapse within the last 3 months
• Voluntary participation with written informed consent

Exclusion Criteria:

• Presence of other neurological, psychiatric, or systemic diseases
• Severe visual, auditory, or balance impairments
• History of surgery within the last 6 months
• Use of sleep medication or central nervous system-affecting drugs
• Severe orthopedic deformity or pain