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| Name | Class |
|---|---|
| Hacettepe University | OTHER |
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The goal of this observational study is to investigate the relationship between sleep quality, cognitive functions, and disease severity in individuals with Parkinson's disease. The main question it aims to answer is:
Is sleep quality associated with cognitive function and disease severity in individuals with Parkinson's disease?
Participants will complete assessments of sleep quality, cognitive function, disease severity, and disease stage during a single evaluation session. Cognitive function will be evaluated using the Stroop Test, Clock Drawing Test, and Montreal Cognitive Assessment. Disease severity will be assessed using the Unified Parkinson's Disease Rating Scale, and disease stage will be determined using the Modified Hoehn and Yahr Scale.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients with Parkinson Disease | Individuals diagnosed with Parkinson's disease who meet the inclusion criteria and undergo assessment of sleep quality, cognitive function, and disease severity. |
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| Measure | Description | Time Frame |
|---|---|---|
| Sleep Quality | Sleep quality will be assessed using the Pittsburgh Sleep Quality Index. Total scores range from 0 to 21, with higher scores indicating poorer sleep quality. | Baseline |
| Stroop Test | Cognitive flexibility and selective attention will be assessed using the Stroop Test. Completion time and error rates will be recorded, with longer times and higher error rates indicating poorer performance. Time Frame: Baseline | Baseline |
| Clock Drawing Test | Visuospatial ability and executive function will be assessed using the Clock Drawing Test. Scores will be recorded based on standard scoring criteria, with lower scores indicating impaired performance. | Baseline |
| Disease Severity | Disease severity will be assessed using the Unified Parkinson's Disease Rating Scale. Higher scores indicate greater disease severity. | Baseline |
| Measure | Description | Time Frame |
|---|---|---|
| Montreal Cognitive Assessment | Global cognitive function will be assessed using the Montreal Cognitive Assessment. Total scores range from 0 to 30, with lower scores indicating greater cognitive impairment. | Baseline |
| Disease Stage |
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Inclusion Criteria:
Exclusion Criteria:
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The study population will consist of individuals aged 40 to 65 years with Parkinson's disease who are followed at the Neurology Outpatient Clinic of Hacettepe University Faculty of Medicine. Participants who meet the eligibility criteria will be invited to participate in the study.
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| Name | Affiliation | Role |
|---|---|---|
| Süleyman Korkusuz | Atılım University | Study Chair |
| Ayla Fil | Hacettepe University | Study Chair |
| Gül Yalçın Çakmaklı | Hacettepe University | Study Chair |
| Büşra Seçkinoğulları Korkusuz | Ankara University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hacettepe University | Ankara | Ankara | 06810 | Turkey (Türkiye) |
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| ID | Term |
|---|---|
| D010300 | Parkinson Disease |
| D007319 | Sleep Initiation and Maintenance Disorders |
| ID | Term |
|---|---|
| D020734 | Parkinsonian Disorders |
| D001480 | Basal Ganglia Diseases |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
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Disease stage will be determined using the Modified Hoehn and Yahr Scale. Higher stages indicate more advanced disease.
| Baseline |
| D009422 | Nervous System Diseases |
| D009069 | Movement Disorders |
| D000080874 | Synucleinopathies |
| D019636 | Neurodegenerative Diseases |
| D020919 | Sleep Disorders, Intrinsic |
| D020920 | Dyssomnias |
| D012893 | Sleep Wake Disorders |
| D001523 | Mental Disorders |