Effect of Motor Function, Depression and Sleep Quality on Attention in Parkinson's Disease

Effect of Motor Function, Depression and Sleep Quality on Attention in Parkinson's Disease

Our study was planned to analyze motor function, endurance and sleep attention information in Parkinson's patients with detailed and objective measurements.

Parkinson's Disease (PD) is a neurodegenerative disease that occurs with the loss of dopaminergic neurons in the basal ganglia (BG) and subsequently affects multiple brain regions. There are studies that evaluate executive functions rather than cognitive functions in Parkinson's patients. However, objective evaluations of the attention parameter are quite rare. Accordingly, our study was planned to examine the effects of motor function, depression and sleep on attention in Parkinson's patients with detailed and objective measurements. Parkinson's patients (n=27) and healthy controls (n=27) aged between 40-85 will be included in the study. Balance evaluation of the individuals participating in the study was carried out by functional reaching test, one-leg standing test and Berg balance scale; Endurance with a 30-second sit-and-stand test; reaction time; with mobile application; muscle strength by hand dynamometer; functional mobility with time up and go test; walking speed, with 10 m walk test; attention with the P300 device; depression, with the Beck depression scale; Sleep quality will be assessed with the Pittsburg sleep questionnaire. At the end of the study, the effects of motor functions, sleep and depression on attention will be examined and compared with healthy controls.

Inclusion Criteria:

• Being 1,2 or 3 according to the Hoehn and yahr scale
• Being between the ages of 40-85
• Being diagnosed with Parkinson's according to UPDS
• Being able to read and write
• Being able to walk independently
• Agreeing to participate in the study after providing detailed information about the research.
• Mini mental test>24

Exclusion Criteria:

• Having severe hearing/visual impairment-loss
• Having an orthopedic, neurological or metabolic disease that may interfere with working
• Having deep brain stimulation applied
• Those with advanced cognitive impairment
• Individuals with dementia
• Patients taking anticholinergic, antidepressive or anxiolytic medications that may affect cognition, and those with other medical or neurological causes that may cause cognitive effects.