After biomechanical preparation of the canals, calcium hydroxide intracanal medicament will be placed inside the canal for one week before obturation.

After biomechanical preparation of the canals, Ledermix intracanal medicament will be placed inside the canal for one week before obturation.

After biomechanical preparation of the canals, Oleanolic acid intracanal medicament will be placed inside the canal for one week before obturation.

Root canal treatments with administration of intracanal medicaments

Absence of discomfort with percussion, Absence of inflammatory exudate from the root canal.

A sample will be taken from the canal to assess the decrease in bacterial count inside the root canal by the effect of intracanal medicament.

A sample will be taken from the periapical region to detect the effect of the intracanal medicaments in reducing inflammation and promoting healing in the periapical region.