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To evaluate the effectiveness of Adductor Canal Block and combined Adductor Canal plus IPACK block in reducing postoperative pain and analgesic requirements in patients undergoing knee surgery.
In total knee arthroplasty, ultrasound-guided Adductor canal block or Adductor Canal block combined with local anesthetic infiltration between the popliteal artery and the capsule of the knee (IPACK) will provide adequate postoperative analgesia.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Adductor canal block group(ACB) | Patients in the ACB group (Group I) will receive a single-shot adductor canal block under ultrasound guidance bupivacaine administered preoperatively. |
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| Adductor canal + iPACK block group(ACB+IPACK) | Patients in the ACB + iPACK group (Group II) will receive a single-shot adductor canal block combined with an infiltration between the popliteal artery and the capsule of the knee (iPACK) under ultrasound guidance bupivacaine. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Adductor Canal Block Group (Group I) | Procedure | All patients in Group I will receive a preoperative adductor canal block. In all groups, an intravenous patient-controlled analgesia device containing morphine will be administered for postoperative pain management. |
| Measure | Description | Time Frame |
|---|---|---|
| opioid consumption | In the recovery room, all patients will given a patient- controlled analgesia device containing morphine 0.5 mg/ml, set to deliver a 1mg bolus dose of morphine with an 15 min lockout time and 4 mg 1 h limit.Total morphine consumption during the 24 hours postoperative period will recorded at 5 times intervals ( 2, 4, 6, 12, 24 hours). | 24 hours after surgery |
| Verbal analog Pain Scores on rest and movement | A Research assistant, blinded to the group allocation, interviewed patients and collected data at 5 times intervals ( 2, 4, 6, 12, 24, hours) in the 24 hours postoperatively. Patients were asked to rate their pain using verbal analog scale, where 0= no pain and 10= worst pain possible. | 24 hours after surgery |
| Measure | Description | Time Frame |
|---|---|---|
| incidences of adverse effects (like nausea and vomiting) | incidences of nausea and vomiting during the 24 hours postoperative period will recorded at 6 time intervals ( 2, 4, 6, 12, 24 hours). | 24 hours after surgery |
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Inclusion Criteria:
Exclusion Criteria:
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Patients aged ≥18 years, classified as ASA physical status I-III, scheduled to undergo total knee arthroplasty.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Sibel Pehlivan, DR | Contact | 0905052532919 | Sibelpehlivan@erciyes.edu.tr |
| Name | Affiliation | Role |
|---|---|---|
| Sibel Pehlivan | Erciyes Üniversitesi | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Sibel Pehlivan | Recruiting | Kayseri | Talas | 38090 | Turkey (Türkiye) |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 38235397 | Result | Shoni M, Samineni AV, Salavati S, Mikkilineni N, Wang A, Abdeen A, Freccero D. Combined Single-Shot Infiltration Between the Popliteal Artery and Capsule of the Knee and Adductor Canal Block With Bupivacaine, Dexmedetomidine, and Dexamethasone for Total Knee Arthroplasty: A Propensity-Matched Analysis. Arthroplast Today. 2023 Dec 28;25:101292. doi: 10.1016/j.artd.2023.101292. eCollection 2024 Feb. | |
| 25154949 |
| Label | URL |
|---|---|
| Combined Single-Shot Infiltration Between the Popliteal Artery and Capsule of the Knee and Adductor Canal Block With Bupivacaine, Dexmedetomidine, and Dexamethasone for Total Knee Arthroplasty: A Propensity-Matched Analysis | View source |
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De-identified individual participant data for all primary and secondary outcome measures will be made available.
Data will be available within 12 months of study completion
Data accept requests will be reviewed by an external independent Review Panel.Requesters will be required to sign a Data Access Agreement.
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| Adductor Canal + iPACK Block Group (Group II)" | Procedure | All patients in Group II will receive a preoperative adductor canal block combined with an iPACK block. Postoperatively, all patients in both groups will be provided with intravenous patient-controlled analgesia containing morphine for pain management. |
|
| Sibel Seckin Pehlivan | Recruiting | Kayseri | 38039 | Turkey (Türkiye) |
|
| Result |
| Mariano ER, Kim TE, Wagner MJ, Funck N, Harrison TK, Walters T, Giori N, Woolson S, Ganaway T, Howard SK. A randomized comparison of proximal and distal ultrasound-guided adductor canal catheter insertion sites for knee arthroplasty. J Ultrasound Med. 2014 Sep;33(9):1653-62. doi: 10.7863/ultra.33.9.1653. |