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This prospective observational study aims to evaluate the pattern, clinical presentation, complications, and short-term outcomes of neonates admitted with gastrointestinal emergencies to the NICU at Assiut University Children Hospital. Data will be collected from admission through discharge, including demographic, antenatal, natal, clinical, nutritional, laboratory, and radiological information, to identify the most common emergencies and factors associated with adverse outcomes.
This prospective observational cohort study will be conducted at the Neonatal Intensive Care Unit (NICU) of Assiut University Children Hospital. The study aims to evaluate the pattern, clinical presentation, complications, and short-term outcomes of neonatal gastrointestinal emergencies.
Eligible neonates will be enrolled consecutively from admission until discharge. Both term and preterm neonates will be included. Data will be systematically collected on demographic characteristics, antenatal and natal history, clinical presentation, feeding practices, laboratory investigations, and radiological findings.
Management approaches, including medical and surgical interventions, will be documented. Patients will be followed throughout their hospital stay to assess outcomes, including recovery, complications, need for surgical intervention, and mortality.
The study also aims to identify the most common types of gastrointestinal emergencies and determine the clinical and demographic factors associated with adverse outcomes among affected neonates.
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| Measure | Description | Time Frame |
|---|---|---|
| Prevalence of the most common gastrointestinal emergencies among neonates admitted to the NICU | The prevalence of each type of neonatal gastrointestinal emergency will be calculated as the proportion of cases among all enrolled neonates admitted to the NICU during the study period. Diagnoses will be based on clinical, laboratory, and radiological findings. | Up to 28 days (hospital stay) |
| Measure | Description | Time Frame |
|---|---|---|
| Mortality Rate | Proportion of neonates who die during hospitalization | Up to 28 days (hospital stay |
| Length of Hospital Stay | Duration of hospitalization in days from NICU admission until discharge or death |
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Inclusion Criteria:
Exclusion Criteria:
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Neonates admitted to the NICU at Assiut University Children Hospital with gastrointestinal emergencies, including both term and preterm infants from 28 weeks gestational age, observed from admission through discharge.
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| ID | Term |
|---|---|
| D020345 | Enterocolitis, Necrotizing |
| D007409 | Intestinal Atresia |
| C562456 | Volvulus Of Midgut |
| D006627 | Hirschsprung Disease |
| D007415 | Intestinal Obstruction |
| ID | Term |
|---|---|
| D004760 | Enterocolitis |
| D005759 | Gastroenteritis |
| D005767 | Gastrointestinal Diseases |
| D004066 | Digestive System Diseases |
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| From admission to discharge, up to 28 days |
| Requirement for surgical intervention | The proportion of neonates requiring surgical management among the enrolled cases. | During hospitalization, up to 28 days |
| D007410 |
| Intestinal Diseases |
| D004065 | Digestive System Abnormalities |
| D000013 | Congenital Abnormalities |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
| D008531 | Megacolon |
| D003108 | Colonic Diseases |