Comparison of the effectiveness of nerve hydrodissection with saline injection of 5% dextrose in carpal tunnel syndrome.

Evaluation of pain, hand function, electrophysiological and ultrasonographic effects when comparing 5% dextrose saline injection via nerve hydrodissection under ultrasound guidance in mild to moderate carpal tunnel syndrome.

Inclusion Criteria:

• Adults aged 18-80 years
• Clinical and electrophysiological diagnosis of mild to moderate carpal tunnel syndrome
• Symptom duration of at least 3 months
• Both male and female participants
• Patients who have not responded adequately to conservative treatment
• Patients who do not wish to undergo surgical treatment
• Ability to provide informed consent

Exclusion Criteria:

• Severe or very severe carpal tunnel syndrome based on EMG findings
• Previous injection therapy for carpal tunnel syndrome
• Prior wrist or carpal tunnel surgery
• Polyneuropathy or other peripheral neuropathies
• Cervical radiculopathy or proximal median nerve entrapment
• Brachial plexopathy or thoracic outlet syndrome
• Pregnancy
• Malignancy
• Local or systemic infection
• Cognitive impairment affecting cooperation
• Systemic diseases affecting the median nerve (e.g., uncontrolled diabetes mellitus, thyroid disorders)