Out-patiente Management for Gangrenous Acute Appendicitis: The PENDI-CSI II Randomized Clinical Trial.

Safety, Efficacy, and Cost-effectiveness of Outpatient Surgery for Gangrenous Acute Appendicitis: The PENDI-CSI II Randomized Clinical Trial.

PHASE II-III CLINICAL TRIAL TO EVALUATE THE SAFETY, EFFECTIVENESS AND EFFICIENCY OF DISCHARGE TO OUTPATIENT SURGERY IN PATIENTS WITH ACUTE GANGRENOUS APPENDICITIS UNDERGOING EMERGENCY SURGERY.

Inclusion Criteria:

• Acute gangrenous appendicitis confirmed during surgery.
• Patient who meets the criteria to be discharged on an outpatient basis
• Signature of informed consent.
• Older than 14 years of age

Exclusion Criteria:

• - Uncomplicated appendectomy.
• Intra-operative purulent or faecaloid peritonitis
• Appendicular abscess or plastron diagnosed by imaging.
• Paralytic ileus preventing oral tolerance.
• Need for placement of abdominal drainage.
• ASA IV and some selected ASA III.
• Immunosuppression.
• Patients with active neoplasia.
• Pregnancy.
• Doubts in the definitive diagnosis.
• Suspicion of inflammatory bowel disease.
• No family support.
• Failure to sign the informed consent form.
• Impossibility to comply with the follow-up.