Adding Effect of Cross-linked Hyaluronic Acid to Microneedling After Coronally Advanced Flap in Isolated RT1 Recession

Evaluation of Gingival Thickness and Root Coverage Outcomes Following Coronally Advanced Flap Combined With Microneedling With or Without Cross-Linked Hyaluronic Acid in RT1 Recession Defects: A Randomized Clinical Trial

In patients with single RT1 recessions and thin gingival phenotype, does adding cross-linked hyaluronic acid by microneedling after CAF surgery produce greater gingival thickness gain and higher probability of complete root coverage at 6 months than microneedling alone?

The aim of this study is to evaluate changes in gingival thickness and root coverage outcomes after coronally advanced flap (CAF) then cross-linked hyaluronic acid injection along with performing microneedling in patients with RT1 single gingival recession with thin gingival phenotype in esthetic region.

1. Inclusion criteria

   • Adult (≥18 years) with Single RT1 gingival recession in esthetic zone.
   • Thin gingival biotype (≤ 1mm).
   • Systemically healthy patients.
   • Non- smoker patients.
   • Full-mouth bleeding on probing (BOP) and plaque indices (PI) scores ≤15%.
   • Willingness to comply with follow up and maintenance.

2. Exclusion criteria

   • RT2 or RT3 recessions or multiple adjacent recessions.
   • Previous mucogingival surgery at the test site.
   • Use of medications causing gingival enlargement.
   • Uncontrolled systemic disease.
   • Pregnancy or lactation.
   • Current smokers.