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| Name | Class |
|---|---|
| SGS proderm GmbH | UNKNOWN |
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The aim of this study is to investigate the impact of a topical product on skin health and aging
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Cosmetic routine | Experimental | The "cosmetic routine" arm will apply the skin care product |
|
| Untreated control | No Intervention | The "Untreated control" arm will not apply the skin care product |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Skin care product | Other | The cosmetic skin care product will be applied twice daily to half of the face |
|
| Measure | Description | Time Frame |
|---|---|---|
| Skin hydration | Change from baseline in skin hydration (assessed on skin capacitance by Corneometer) after 2 and 8 weeks | 8 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Anti-wrinkle efficacy | Change from baseline in anti-wrinkles efficacy (assessed on three-dimensional structure of the wrinkles in the periorbital regions) after 2 and 8 weeks. Anti-wrinkle efficacy will be assessed using DermaTOP. Parameters measured: Rz and Ra, representing mainly the rough structure (Rz) or the finer skin structure (Ra). | 8 weeks |
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INCLUSION CRITERIA
Exclusion criteria
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| SGS proderm GmbH | Schenefeld | 22869 | Germany |
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Split-face design. Subjects will be divided equally in 2 treatment groups (topical product or untreated). Treatments will be randomly and balanced assigned to left and right test area.
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Double (Outcomes Assessor)
| Skin barrier function | Change from baseline in skin barrier function (assessed onTransepidermal water loss (TEWL) by Tewameter [g/(m²h)]) after 2 and 8 weeks | 8 weeks |
| Skin firmness | Change from baseline in skin firmness (assessed by R0 (Uf) by Cutometer [mm]) after 2 and 8 weeks | 8 weeks |
| Skin elasticity | Change from baseline in skin elasticity (assessed by R7 (Ur/Uf) by Cutometer) after 2 and 8 weeks | 8 weeks |
| Clinical skin appearance | Change from baseline for skin appearance (assessed on VISIA-CR Image analysis) after 2 and 8 weeks | 8 weeks |
| Skin aging hallmarks | Change from baseline in skin hallmarks of aging (assessed on 22mm D-Squames® tape strips) after 2 and 8 weeks | 8 weeks |
| Product traits | Subjective evaluation of product traits assessed via questionnaire after 2 and 8 weeks. Product traits will be assessed by the subjects with a list of closed questions with the following predefined identical options to tick: 2 = Fully disagree; 1 = Rather disagree;
| 8 weeks |
| Clinical Before-After Photography | An additional cohort of 15 participants will apply the test product to their full face. Trained graders will analyze images (assessed on VISIA-CR Image) to visually determine biological skin age after 2 and 8 weeks. | 8 weeks |