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| Name | Class |
|---|---|
| proDERM GmbH | INDUSTRY |
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The purpose of this study is to assess the anti-aging and reduction of dark circles efficacy of a cosmetic product after 8 weeks of application.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Face care product (Eye cream) | Experimental | Comparison between assessment times. Assessments will be performed before, after 2, 4 and 8 weeks of product application. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Face care product (Eye cream) | Other | The test material(s) will be cosmetic products to be applied around the eye region on both sides of the face daily. The test product will be applied twice daily in the morning and in the evening by the subjects |
| Measure | Description | Time Frame |
|---|---|---|
| Anti-wrinkle efficacy will be assessed in the periorbital regions wrinkles using DermaTOP. Parameters measured: Rz and Ra, representing mainly the rough structure (Rz) or the finer skin structure (Ra). | 8-weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Change from baseline in skin firmness by Cutometer [mm] after 2, 4 and 8 weeks | 8-weeks | |
| Change from baseline in skin elasticity by Cutometer after 2, 4 and 8 weeks | 8-weeks | |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Christiane Röck, Dipl. Biol | SGS proderm GmbH | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| proderm GmbH | Schenefeld | Germany |
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Intra-individual comparison
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Blinding of sponsor label (de-branded product)
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| Change from baseline in skin hydration (assessed on skin capacitance by Corneometer [a.u.]) after 2, 4 and 8 weeks |
| 8-weeks |
| Change from baseline in skin barrier function (assessed on transepidermal waterloss by Tewameter [g/(m²h)]) after 2, 4, 8-weeks | 8-weeks |
| Dark circles color in difference by ColorFace image analysis Clinical assessment of dark circle reduction around the eye area by trained grader | 8-weeks |
| Clinical assessment of dark circle reduction by trained grader | 8-weeks |
| Subjective Evaluation of product traits assessed via questionnaire after 2, 4 and 8 weeks | 8-weeks |
| Assessment of eye area puffiness by photo ranking by 3 trained graders | 8-weeks |
| Photo documentation of skin by ColorFace | 8-weeks |