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| Name | Class |
|---|---|
| Princeton Consumer Research | OTHER |
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The objective of this study is to determine the efficacy of four topical products to improve facial skin longevity over an eight-week use period utilizing analysis of images and self-perception questionnaires.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Face care product (eye cream) | Experimental | The topical product (eye cream) containing Mitopure will be used for eight weeks. |
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| Face care product (cream A) | Experimental | The topical product (moisturizing formula A) containing Mitopure will be used for eight weeks. |
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| Face care product (cream B) | Experimental | The topical product (moisturizing formula B) containing Mitopure will be used for eight weeks. |
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| Face care product (serum) | Experimental | The topical product (serum) containing Mitopure will be used for eight weeks. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Face care product | Other | The topical product will be applied twice daily (morning and night). |
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| Measure | Description | Time Frame |
|---|---|---|
| Product Acceptance | Product Acceptance will be evaluated via questionnaire (measurement tool) responses after eight weeks of product use (time frame) and quantified as a single percentage score (unit of measure=%; minimum value=0%; maximum value=100%) so higher scores (closer to 100%) represent better Product Acceptance. Participants will respond to 12 closed questions by ticking one of four predefined options: -2=Fully disagree; -1=Rather disagree; 1=Rather agree; 2=Fully agree. For each question, every participant's response will be categorized as "disagree" (scores -2, -1) or "agree" (scores 1, 2). The percentage of participants that respond "agree" will be calculated ([number of "agree" responses/total number of responses]*100%), yielding one overall "agreement" value (unit of measure = %) for each of the 12 questions. Product Acceptance will be calculated by averaging the 12 overall "agreement" values. Clear product acceptance will be determined if the Product Acceptance score is at least 70%. | 8 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Skin wrinkles | Three-dimensional facial images will be taken with Phaseshift Rapid In vivo Measurement Of the Skin (PRIMOS) at baseline, week 4, and week 8 and will be analyzed for skin wrinkle size (unit of measure is millimeters). | 8 weeks |
| Haut AI Facial Analysis |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Nalini Kaul, PhD | Princeton Consumer Research Corp. | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Princeton Consumer Research Corp. | Winnipeg | Manitoba | R3L 0J4 | Canada |
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| Face care product | Other | The topical product will be applied twice daily (morning and night). |
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| Face care product | Other | The topical product will be applied twice daily (morning and night). |
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| Face care product | Other | The topical product will be applied twice daily (morning and night). |
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High resolution digital facial VISIA images will be taken of right side, left side and front of the face with VISIA® CRP-GEN 5 at baseline, week 4, and week 8. The front face image will be analyzed by Haut AI for overall facial age health score (scale of 0 to 100, in which higher score represents better outcome). |
| 8 weeks |
| Self-perceived product traits | Subjective evaluation of 12 product traits assessed via questionnaire after 4 and 8 weeks. Product traits will be assessed by the subjects with a list of closed questions with the following predefined identical options to tick: -2 = Fully disagree; -1 = Rather disagree; 1 = Rather agree; 2 = Fully agree. Self-perceived product trait will be calculated for each of the 12 product traits independently. For each trait, total percentages resulting in at least 80% agreement will represent a clear level of agreement and opinion of the panel. Frequencies between 70% to 80% will represent a high level of agreement. Less than 70% agreement will represent constrained and undecided agreement. | 8 weeks |
| Adverse Events | 8 weeks |