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Lower abdominal surgeries cause significant pain and can be managed by injecting local anesthetic agents between muscles of abdominal wall that can provide post operative pain relief and its duration can be prolonged by adding drugs to local anesthetic regimen
TAPP block can provide significant post operative analgesia following lower abdominal surgery and its duration can be prolonged by adding adjuvants to local anesthetics.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Dexmedetomidine | Active Comparator |
| |
| Dexamethasone | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Dexmedetomidine | Drug | 20 ml 0.25% Bupivacaine along with 0.5 Mcg/kg of Dexmedetomidine will be given in TAPP block bilaterally |
|
| Measure | Description | Time Frame |
|---|---|---|
| Resuce analgesia | Time in the post operative period when patient first demands rescues analgesia will be noted in minutes |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Department of Anesthesia Principal Investigator | Contact | +92-333-5236956 | departmentofanesthesiapims@gmail.com | |
| Muhammad Haroon Anwar Study Coordinator, MBBS | Contact | +92-333-5236956 | haroonanwar22@gmail.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Pakistan Institute of Medical Sciences Islamabad | Recruiting | Islamabad | Federal | 44000 | Pakistan |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| Background | Sobhy YS, Gadalla RR, Nofal WH, Saleh MAE, Abdou KM. A comparative study between the use of dexmedetomidine .vs dexamethasone as adjuvants to bupivacaine in ultrasound-guided transversus abdominis plane block for postoperative pain relief in patients undergoing lower abdominal surgeries. Anaesth. pain intensive care 2022;26(5):681-688 |
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Hospital Ethical Committe doesnt allow
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| Dexamethasone | Drug | 20 ml 0.25% Bupivacaine along with 4 mg of Dexamethasone will be given in TAPP block bilaterally |
|
| ID | Term |
|---|---|
| D020927 | Dexmedetomidine |
| D003907 | Dexamethasone |
| ID | Term |
|---|---|
| D007093 | Imidazoles |
| D001393 | Azoles |
| D006573 | Heterocyclic Compounds, 1-Ring |
| D006571 | Heterocyclic Compounds |
| D011246 | Pregnadienetriols |
| D011245 | Pregnadienes |
| D011278 | Pregnanes |
| D013256 | Steroids |
| D000072473 | Fused-Ring Compounds |
| D011083 | Polycyclic Compounds |
| D013259 | Steroids, Fluorinated |
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