Examine the Epidemiology and Outcomes of Transitions From PD-to-HD in Canada

Understand, Plan and Improve Care and Wellbeing of Patients at High Risk of Transfer From Peritoneal Dialysis to Hemodialysis, Epidemiology (Phase 1)

Transitions from peritoneal dialysis to hemodialysis are common during kidney replacement therapy and may be associated with adverse outcomes. However, the incidence, predictors, and outcomes of PD-to-HD transitions at a national level remain incompletely characterized.

This study will use Canadian dialysis and hospitalization databases to examine the epidemiology and outcomes of PD-to-HD transitions among adults initiating dialysis in Canada. The study will evaluate transition incidence, predictors, and post-transition outcomes including mortality, transplantation, modality changes, and hospitalizations.

Inclusion Criteria:

• Adults (≥18 years)
• Dialysis initiation in Canada between January 1, 2005 and December 31, 2018
• Peritoneal dialysis duration >30 consecutive days

Exclusion Criteria:

• Dialysis initiation in Quebec or Manitoba during the study period
• Dialysis initiation in a foreign country
• Missing data on initial dialysis modality
• Pre-emptive kidney transplantation