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| ID | Type | Description | Link |
|---|---|---|---|
| 2025-A02030-49 | Other Identifier | IDRCB |
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| Name | Class |
|---|---|
| Université de Lille | OTHER |
| Breast Cancer Research Foundation | OTHER |
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Women in the Hauts-de-France region show higher breast cancer mortality despite no overall higher incidence, suggesting differences in the care pathway. This multicenter study will describe the overall time from the first warning sign to initiation of the first treatment, and will break down this delay into three consecutive intervals (symptoms to mammography, mammography to biopsy, biopsy to first treatment). Participants will complete a one-time questionnaire (up to 1 hour, with assistance if needed), and clinical data will be extracted in a standardized way from medical records (key dates and tumor characteristics). A random sample of 10% of incident breast cancer cases identified by each hospital information department will be used to ensure balanced geographic representation across 38 centers. The study will also explore how individual and contextual factors (psychological, behavioral, socio-demographic, access to care, communication) are associated with each time interval, and exploratory analyses will assess links with severity (metastases and prognostic score).
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| Measure | Description | Time Frame |
|---|---|---|
| Total time from first warning sign to initiation of first treatment. | One-time assessment using patient-reported dates and medical record dates at inclusion (single questionnaire session + record extraction). Questionnaire time : around 1 hour |
| Measure | Description | Time Frame |
|---|---|---|
| Time from first warning sign to first mammography | At inclusion, one-time assessment using patient-reported dates and medical record dates. | |
| Time from mammography to biopsy. | At inclusion, one-time assessment using patient-reported dates and medical record dates. |
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Inclusion Criteria:
Exclusion Criteria:
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Adult women with recently diagnosed invasive breast carcinoma, receiving care in a participating Hauts-de-France center.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Clinique Ste Isabelle | Abbeville | 80100 | France | |||
| CHU Amiens |
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| Time from biopsy to initiation of first treatment. | At inclusion, one-time assessment using patient-reported dates and medical record dates. |
| To evaluate breast cancer severity at diagnostic. Severity will be assessed by the presence of metastatic disease at diagnosis, recorded as a binary outcome (yes/no) indicating the rate of metastatic at diagnosis | At inclusion, assessed from medical record extraction. |
| To evaluate patients with localized breast cancer, by pronosis estimated using the PREDIC Breast tool. | Pronosis will be reported as 5-year and 10 year estimated survival probabilities, calculated from clinical variables extrected from the medical record at inclusion and expressed on a 0 to 100 % scale, with higher values indicating a better predicted outcome. | At inclusion, calculated using clinical variables extracted from the medical record |
| Amiens |
| 80054 |
| France |
| Clinique Victor Pauchet | Amiens | 80090 | France |
| Centre Marie Curie | Arras | 62000 | France |
| Hôpital privé Les Bonnettes | Arras | 62000 | France |
| CH Beauvais | Beauvais | 60000 | France |
| Centre Pierre Curie | Beuvry | 62321 | France |
| CH Bethune | Béthune | 62408 | France |
| CH Boulogne | Boulogne | 62321 | France |
| CH Calais | Calais | 62107 | France |
| CH Chauny | Chauny | 02300 | France |
| Centre de Radiothérapie de Compiègne | Compiègne | 60200 | France |
| Polyclinique St Côme | Compiègne | 60200 | France |
| CH Compiègne | Compiègne | 60321 | France |
| Clinique de Flandre | Coudekerque-Branche | 59210 | France |
| Centre de Radiothérapie de Creil | Creil | 60100 | France |
| Centre Leonard de Vinci | Dechy | 59187 | France |
| Polyclinique de la Clarence | Divion | 62460 | France |
| Institut Andrée Dutreix | Dunkirk | 59240 | France |
| CH Dunkerque | Dunkirk | 59385 | France |
| Polyclinique d'Hénin-Beaumont | Hénin-Beaumont | 62254 | France |
| CH Lens | Lens | 62300 | France |
| Centre Oscar Lambret | Lille | 59000 | France |
| Hôpital privé Le Bois | Lille | 59000 | France |
| Hôpital St Vincent | Lille | 59000 | France |
| CHU Lille | Lille | 59037 | France |
| Centre Gray | Maubeuge | 59600 | France |
| CH Roubaix | Roubaix | 59100 | France |
| CH St Quentin | Saint-Quentin | 02321 | France |
| CH Soissons | Soissons | 02200 | France |
| Clinique de la Victoire | Tourcoing | 59200 | France |
| CH Tourcoing | Tourcoing | 59208 | France |
| Clinique des dentellières | Valenciennes | 59300 | France |
| CH Valenciennes | Valenciennes | 59322 | France |
| ID | Term |
|---|---|
| D001943 | Breast Neoplasms |
| ID | Term |
|---|---|
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D001941 | Breast Diseases |
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
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