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| ID | Type | Description | Link |
|---|---|---|---|
| CSE-24-08_PASSAGE | Other Identifier | Institutional Review Board (IRB) of the AP-HP's Clinical Data Warehouse (CDW) |
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| Name | Class |
|---|---|
| Inria, the French National Institute for computer science and applied mathematics | UNKNOWN |
| CentraleSupelec School of Engineering | UNKNOWN |
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More than half of new cases of cancer in Europe in 2022 occurred in people aged over 70. In addition to cancer, the majority of older people have one or more illnesses that may interact with the treatment decision, cancer progression, tolerance and efficacy of treatments, quality of life, care pathway and survival. Furthermore, cancer treatments are most often evaluated in middle-aged subjects without severe disease, so the real-life management of older patients is often empirical.
The general objective of the PASSAGE project is to assess the hospital care pathways of older patients with cancer treated at AP-HP by evaluating key elements of these pathways from both geriatric and therapeutic perspectives. Characterizing these care trajectories will help identify the most vulnerable patient profiles and potential disparities in access to care, with the goal of optimizing the management of elderly patients with cancer.
The aims of this research are 1) to provide a better description of trends in the management of older cancer patients in routine clinical practice, and 2) to assess the impact of frailty, multimorbidity and the management of these patients on the prognosis of the disease.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients aged 70 or over with solid cancer | The following inclusion criteria will be applied to identify the study population:
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| Measure | Description | Time Frame |
|---|---|---|
| type of care pathway | The primary endpoint is the type of care pathway as identified by longitudinal clustering analysis of Electronic Health Record (EHR) data in the year following diagnosis (medical diagnoses, procedures, admissions, treatment received),. | from cancer diagnosis during a year of follow-up |
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Inclusion Criteria:
Exclusion Criteria:
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elderly cancer patients treated at AP-HP
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Henri Mondor Hospital | Créteil | VAL DE Marne | 94010 | France |
Data are available upon reasonable request. Proposals should be directed to ASSISTANCE PUBLIQUE HOPITAUX DE PARIS (AP-HP), Department for Clinical Research, Innovation (DRCI) represented by Mr Milan LAZAREVIC , Director. To gain access, data requestors will need to sign a data transfert agreement with the sponsor
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| ID | Term |
|---|---|
| D009369 | Neoplasms |
| D000073496 | Frailty |
| ID | Term |
|---|---|
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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