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This study compares the effectiveness of a Transversus Abdominis Plane (TAP) block in reducing post-operative pain for patients undergoing laparoscopic cholecystectomy. Sixty patients were divided into two groups: one group received a TAP block with a local anesthetic at the end of surgery, and the control group did not. The main goal was to see if the TAP block significantly lowers pain scores (measured on a scale of 0 to 10) within the first 12 hours after surgery and if it reduces the need for additional pain-relief medications.
Laparoscopic cholecystectomy is the gold standard for treating symptomatic cholelithiasis; however, patients often experience significant in the early post-operative period. This randomized controlled trial (RCT) was conducted at the Department of Surgery, Liaquat College of Medicine & Dentistry, Karachi, to evaluate the analgesic efficacy of the TAP block.
A total of 60 patients, aged 18-60 years with ASA I or II, were randomized into two equal groups (n=30 each). The intervention group received an TAP block while the control group received standard post-operative analgesia.
The primary objective was to compare the mean Visual Analog Scale (VAS) score at 12 hours post-operation. Secondary objectives included assessing the time to the first request for rescue analgesia and the type of analgesic drug used. Data were analyzed to determine if the TAP block provides superior pain control compared to conventional methods.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| TAP Block Group | Experimental | Patients in this group received a Transversus Abdominis Plane (TAP) block at the end of the laparoscopic cholecystectomy but before extubation. |
|
| Control Group (The No TAP Block Group) | Other | Patients in this group underwent laparoscopic cholecystectomy under the same general anesthesia protocol but did not receive a TAP block |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Bupivacaine 0.25% | Drug | Transversus Abdominis Plane (TAP) block administered by injecting 20ml of 0.25% Bupivacaine between the internal oblique and transversus abdominis muscles. |
| Measure | Description | Time Frame |
|---|---|---|
| Visual Analog Scale (VAS) Score for Pain | A subjective psychometric response scale used to measure pain intensity. It consists of a 10 cm line where 0 represents "no pain" and 10 represents "the worst pain imaginable.". | 12 hours post-operation |
| Measure | Description | Time Frame |
|---|---|---|
| Time for First Request of Rescue Analgesia | The duration of time (in hours or minutes) from the end of the surgical procedure until the patient first requests additional pain medication due to inadequate pain control. | Within the first 24 hours post-operation. |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Darul Sehat Hospital- Liaquat College of Medicine & Dentistry. | Karachi | Pakistan |
There is no plan to share individual participant data at this time
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| ID | Term |
|---|---|
| D002769 | Cholelithiasis |
| D010149 | Pain, Postoperative |
| ID | Term |
|---|---|
| D001660 | Biliary Tract Diseases |
| D004066 | Digestive System Diseases |
| D011183 | Postoperative Complications |
| D010335 | Pathologic Processes |
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| Standard Post-Operative Care | Other | Patients received the routine post-operative analgesia protocol of the hospital (e.g., IV Ketorolac or Paracetamol) without the administration of a TAP block |
|
| D013568 | Pathological Conditions, Signs and Symptoms |
| D010146 | Pain |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |