Adverse Effects of ATG/ALG Therapy in Aplastic Anemia

A Study on the Dynamics and Grading Criteria Construction of Adverse Reactions to ATG/ALG Therapy in Aplastic Anemia

This prospective, single-center, observational cohort study aims to systematically observe and describe the clinical characteristics of adverse reactions in patients with aplastic anemia undergoing ATG (Anti-Thymocyte Globulin) /ALG (Anti-Lymphocyte Globulin) treatment, providing a data foundation for the development of relevant management strategies. This study plans to enroll 200 aplastic anemia patients undergoing ATG/ALG treatment

Inclusion Criteria:

• Meet the diagnostic criteria for aplastic anemia (Camitta criteria);
• Receiving ATG/ALG immunosuppressive therapy for the first time;

Exclusion Criteria:

• Previously received hematopoietic stem cell transplantation;
• Aplastic anemia patients receiving ATG/ALG as part of transplant conditioning regimen;