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in this study investigators do revascularization technique to promote root growth of immature mandibular first permanent molar by using CGF and PRF from blood sample of patients
children 6-8 yrs were selected for this study because the roots of mandibular first permanent molar is not completed. then access cavity is opened, irrigation protocol is applied, intracanal medication is applied and the cavity is sealed with temporary filling. after three weeks blood sample is obtained from patients to get CGF and PRF membranes. temporary filling is removed . intracanal medication is removed, over instrumentation is done to get some intracanal blood the wait tell blood clot is formed then CGF or PRF is applied on the clot the bio dentine is applied and cavity is sealed with composite restoration
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| CGF and biodentine arm | Active Comparator | (control group) Which CGF and bio-dentine are applied to the immature pulp of the first permanent molar |
|
| PRF and biodentine arm | Active Comparator | PRF and bio-dentine are applied on immature pulp of first permanent molar |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Revascularization/Conservative management | Biological | Compare the effect of CGF and PRF in the revascularization of immature mandibular first permanent molar using bio-dentine |
| Measure | Description | Time Frame |
|---|---|---|
| root growth | change root length | 18 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Ahmed elheeny, professor of Pediatric and Com | unaffilliaed | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faculty of Dentistry Minya University | Minya | Minya Governorate | 2422998 | Egypt |
CONCENTRATED GROWTH FACTOR VERSUS PLATELETS-RICH FIBRIN IN REVASCULARIZATION OF IMMATURE NECROTIC MANDIBULAR FIRST PERMANENT MOLAR
2027
dental students and researchers in denta field
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| Type | Includes Protocol | Includes SAP | Includes ICF | Document Label | Document Date | Document Uploaded Date | Document File Name |
|---|---|---|---|---|---|---|---|
| Prot | Yes | No | No | Study Protocol | Jan 10, 2025 | Feb 19, 2026 |
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parallel randomized controlled study
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| Prot_000.pdf |
| ICF | No | No | Yes | Informed Consent Form | Jul 28, 2025 | Mar 4, 2026 | ICF_001.pdf |
| ID | Term |
|---|---|
| D000072700 | Conservative Treatment |
| ID | Term |
|---|---|
| D013812 | Therapeutics |
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