A Cohort Study on Obese Patients' Multidisciplinary Integ... | NCT07451938

Studies
A Cohort Study on Obese Patients' Multidisciplinary Integrated Health Management

NCT07451938

Sponsor

China-Japan Friendship Hospital

Status

Completed

Last Update Posted

Mar 5, 2026Actual

Enrollment

1,500Actual

Phase

Not provided

Conditions

Obesity
Diabete Type 2
Bariatric Surgery

Interventions

Bariatric surgery
Non-surgical threapy

Countries

China

Protocol Section

Identification Module Status Module Sponsor/Collaborators Module Oversight Module Description Module Conditions Module Design Module Arms/Interventions Module Outcomes Module Eligibility Module Contacts/Locations Module References Module IPD Sharing Statement Module

Results Section

Participant Flow Module Baseline Characteristics Module Outcome Measures Module Adverse Events Module More Info Module

Annotation Section

Annotation Module

Document Section

Large Document Module

Derived Section

Miscellaneous Info Module Condition Browse Module Intervention Browse Module

Protocol Section

Identification Module

NCT ID

Results Section

No data available

No data is available for this block.

Annotation Section

No data available

No data is available for this block.

Document Section

No data available

No data is available for this block.

Derived Section

Miscellaneous Info Module

Version Holder

Status Module

Record Verification Date

Nov 2025

Overall Recruitment Status or Expanded Access Status

Completed

Last Known Status

Not provided

Delayed Posting

Not provided

Why Stopped

Not provided

Expanded Access Info

Start Date

Jul 1, 2017Actual

Primary Completion Date

Jul 30, 2025Actual

Completion Date

Jul 30, 2025Actual

First Submitted Date

May 16, 2024

First Submission Date that Met QC Criteria

Feb 28, 2026

First Posted Date

Mar 5, 2026Actual

Results Waived

Not provided

Results First Submitted Date

Not provided

Results First Submitted that Met QC Criteria

Not provided

Results First Posted Date

Not provided

Certification/Extension (aka Delayed Results) First Submitted Date

Not provided

Certification/Extension First Submitted that Passed QC Review

Not provided

Certification/Extension First Posted Date

Not provided

Last Update Submitted Date

Feb 28, 2026

Last Update Posted Date

Mar 5, 2026Actual

Sponsor/Collaborators Module

Responsible Party, by Official Title

Hua Meng, Director of the General Surgery Department & Obesity and Metabolic Disease Center of China-Japan Friendship Hospital, China-Japan Friendship HospitalPrincipal Investigator

Lead Sponsor

China-Japan Friendship HospitalOTHER

Collaborators

Not provided

Oversight Module

Has Data Monitoring Committee (DMC)

Not provided

Is FDA Regulated Drug

Is FDA Regulated Device

Is Unapproved Device

Not provided

Pediatric Postmarket Surveillance of a Device Product

Not provided

Product Exported from US

Not provided

FDAAA801 Violation

Not provided

Description Module

Brief Summary

To explore influencing factors of diabetes remission and recovery of other complications after bariatric surgery. We design a multicenter study including respective cohort and prorespective cohort of obese patients treated with bariatric surgery or non-bariatric surgery，and collect clinical parameters and laboratory indicators.

Detailed Description

Not provided

Design Module

Study Type

Observational

Number of References to an Expanded Access Study

Not provided

Expanded Access Types

Not provided

Patient Registry

Target Follow-Up Duration

Not provided

Phases

Not provided

Interventional Study Design

Allocation

Not provided

Intervention Model

Biospecimen

No data available

No data is available for this block.

Enrollment

1,500Actual

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
Surgical group			Procedure: Bariatric surgery Other: Non-surgical threapy
Non-surgical group			Other: Non-surgical threapy

Interventions

Name	Type	Description	Arm Group Labels	Other Names
Bariatric surgery	Procedure	Laparoscopic sleeve gastrectomy or laparoscopic gastric bypass based on β-cell function	Surgical group

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
Total weight loss		1st, 3rd, 6th and 12th month after intervention, respectively.

Secondary Outcomes

Measure	Description	Time Frame
Fasting blood glucose		1st, 3rd, 6th and 12th month after intervention, respectively.
Average blood glucose from continuous glucose monitoring		1st, 3rd, 6th and 12th month after intervention, respectively.

Other Outcomes

Not provided

Eligibility Module

Eligibility Criteria

Inclusion Criteria:

Age range from 12 to 75 years,
BMI (Body Mass Index) ≥ 25.0 kg/m2,

Exclusion Criteria:

Type 1 diabetes,
Severe liver or kidney disease (eGFR < 30 ml/min), malignant tumors, endocrine disorders such as thyroid or Cushing's syndrome, acute coronary syndrome, uncontrolled heart failure, pregnancy or lactation, pancreatitis,
Contraindications to other surgeries or medications.

Accepts Healthy Volunteers

Sex

All

Sex/Gender Based

Not provided

Sex/Gender Description

Not provided

Minimum Age

12 Years

Maximum Age

75 Years

Standard Ages

ChildAdultOlder Adult

Study Population

Obese patients treated with bariatric surgery or non-bariatric surgery(diet, exercise and weight loss drugs)

Sampling Method

Non-Probability Sample

Contacts/Locations Module

Central Contacts

Not provided

Overall Officials

Name	Affiliation	Role
Hua Meng	China-Japan Friendship Hospital	Principal Investigator

Locations

Facility	Status	City	State	ZIP	Country	Contacts
China-Japan Friendship Hospital		Beijing			China

Condition Browse Module

MeSH Terms

ID	Term
D009765	Obesity
D003924	Diabetes Mellitus, Type 2

Ancestor Terms

ID	Term
D050177	Overweight
D044343	Overnutrition
D009748	Nutrition Disorders
D009750	Nutritional and Metabolic Diseases

Browse Leaves

Not provided

Browse Branches

Not provided

Intervention Browse Module

MeSH Terms

ID	Term
D050110	Bariatric Surgery

Ancestor Terms

ID	Term
D049088	Bariatrics
D000073319	Obesity Management
D013812	Therapeutics
D013514	Surgical Procedures, Operative

Browse Leaves

Not provided

Browse Branches

Not provided