A Cohort Study on the Efficacy of Bariatric Surgery for Rapidly Progressing Diabetic Nephropathy

A Cohort Study on the Efficacy of Bariatric Surgery for Rapidly Progressing Diabetic Nephropathy

Establish a cohort of diabetic kidney disease(DKD) patients with intensive weight loss treatment to evaluate the impact of intensive weight loss treatment on the renal prognosis of DKD and construct a prediction model for the improvement of renal outcomes after weight loss.

Inclusion Criteria:

• Age 18 to 65 years old;

  • BMI>25Kg/m2 or abdominal obesity (i.e. waist circumference>90cm for men and>85cm for women);

    • eGFR<30ml/min/1.73m2 or urinary microalbumin≥300mg/g, eGFR<60ml/min/1.73m2.

Exclusion Criteria:

• Patients who are taking glucocorticoids;

  • Combined with tumors; ③Combined with autoimmune diseases; ④Serum albumin<25g/L.