Analysis of Effects of High-intensity Physical Exercise in Subjects With Dialyzed Chronic Kidney Disease and in Conservative Treatment

Effect of Exercise in Patients With Chronic Kidney Disease: TONE Trial

This study aims to analyze the effects of physical activity in patients with chronic kidney disease undergoing dialysis or conservative treatment. Patients will be randomized into two groups: combined exercise (high-intensity aerobic resistance + strength training) and control group

Inclusion Criteria:

• Signature of the informed consent
• Patients with CKD stage 1 to 5 under conservative treatment
• Patients undergoing chronic hemodialysis for at least 3 months
• Age ≥ 18

Exclusion Criteria:

• Severe cardiovascular disease (NYHA class IV or hypertension class III)
• TIA or myocardial ischemia within the last three months
• Anatomical limitations
• Health conditions detected during the stress test (CPET)