Comparison Of Clinical Outcomes of Intraperitoneal Bupivacaine Instillation Versus Placebo as Preemptive Analgesia in Patients Undergoing Open Appendectomy

Comparison Of Clinical Outcomes of Intraperitoneal Bupivacaine Instillation Versus Placebo as Preemptive Analgesia in Patients Undergoing Open Appendectomy

To compare the clinical outcomes of intraperitoneal bupivacaine instillation vs placebo as preemptive analgesia in patients undergoing open appendectomy

Inclusion Criteria:

• Patients presenting to the emergency department undergoing open appendectomy.

Exclusion Criteria:

• Patients undergoing interval appendectomy or having perforated appendix as evident by examination (abdominal tenderness/ fever) and USG findings (presence of abscess, fluid collection, or free air).
• Uncontrolled medical disease (DM: BSL >200mg/dl, HTN: BP >140/90)
• History of chronic kidney or liver disease/ psychiatric illness/ Active peptic ulcer disease (as determined on history and medical records)
• Alcoholics
• History of chronic pain or patients on analgesic medications
• Pregnant females
• History of allergy to bupivacaine/ ketorolac as determined on history
• Children, Adolescents and patients with mental illness.