Probiotics, Antibiotics and the Post-Antibiotic Microbiota

Probiotics, Antibiotics and the Post-Antibiotic Microbiota

Antibiotic therapy can cause gastrointestinal dysbiosis and this study will assess the impact of probiotic supplementation on microbiological composition and functionality pre- and post- antibiotic therapy

Inclusion Criteria:

1. Adults, aged 18-40.
2. Been prescribed an oral dose of cephalosporin antibiotic lasting 5 - 10 days.
3. Willing to provide stool samples and, for women, vaginal samples.
4. Willing to avoid consumption of any other probiotic capsules/tablets during the study.

Exclusion Criteria:

1. If antibiotics prescribed are intended to treat any gastrointestinal or vaginally related issue.
2. Any antibiotic intake within the last 3 months.
3. Immunodeficient or undergoing immunosuppressive therapy.
4. Currently diagnosed with diabetes/cardiovascular disease/cancer/dementia.
5. Any unexplained loss of weight in recent months.
6. Known to be pregnant or <3 months postpartum.