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| Name | Class |
|---|---|
| Weizmann Institute of Science | OTHER |
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The investigators would like to examine the extent of gut microbiome rehabilitation in healthy people after the consumption of antibiotics.
Outcomes of probiotic treatment versus bacteriotherapy will be compared.
The investigators would like to examine the extent of rehabilitation of the composition and functioning of the intestinal bacteria in healthy people after the consumption of antibiotics.
Since the digestive mocus enables the connection between the host and the bacteria that live within it, the investigators would like to characterize the microbiome in the different areas along the digestive system - before antibiotic treatment and after rehabilitation by probiotic treatment versus bacteriotherapy.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| No intervention | No Intervention | No intervention after antibiotic treatment. | |
| Probiotic microbiome rehabilitation | Active Comparator | Probiotic treatment after antibiotic treatment. |
|
| Bacteriotherapy microbiome rehabilitation | Active Comparator | Bacteriotherapy after antibiotic treatment. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Probiotic treatment | Dietary Supplement | 4 weeks of probiotic treatment after 7 days of antibiotics (Metronidazole+Ciprofloxacin) |
|
| Measure | Description | Time Frame |
|---|---|---|
| Microbiome composition | stool samples | 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| Microbiome composition | Gastrointestinal tract biopsies | 1 month |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Noya Horowitz, PhD | Contact | 97236974297 | noyah@tlvmc.gov.il |
| Name | Affiliation | Role |
|---|---|---|
| Zamir Halpern, MD | Tel-Aviv Sourasky Medical Center | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Gastroentherology | Recruiting | Tel Aviv | 64239 | Israel |
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| Bacteriotherapy | Biological | Bacteriotherapy (autologous fecal microbiota transplantation) after 7 days of antibiotics (Metronidazole+Ciprofloxacin) |
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