A Pilot Trial of Chinese Medicine for Patients With Dialytic Hypotension

A Pilot Randomized Waitlist-controlled Trial of a Zheng-based Chinese Medicine Intervention for Patients With Dialytic Hypotension in Taiwan

To evaluate the epidemiological status of traditional Chinese Medicine (TCM) constitution in patients with dialytic hypotension, and design a clinical study based on a Zheng-based herbal formulation to evaluate the clinical efficacy and safety of TCM

Inclusion Criteria:

• Maintenance bicarbonate hemodialysis (HD) for more than 1 year, three times a week 3.5 to 4.5 h HD schedule.
• Have experienced more than 30% episodes of IDH (defined as a systolic BP<90 mmHg on dialysis or requirement for clinical intervention) during the exposure assessment period (months 1-3) of this study
• Cognitive ability to give written informed consent.

Exclusion Criteria:

• Allergic history to Chinese herbal medicine
• Systemic diseases such as coagulation disorders, malignancy, liver diseases and cardiovascular diseases.
• Estimated survival time < 1 year.
• Mental illness.
• Participate in other clinical trials.