Detailed Description Human papillomavirus (HPV) is one of the leading causes of cervical cancer and can be prevented by vaccination. However, HPV vaccination rates among young women are low, largely due to insufficient knowledge and misconceptions about HPV and the vaccine. Therefore, an effective educational program may improve both knowledge and vaccination intention.

The aim of this randomized controlled trial is to examine the effect of delivering HPV education through different methods (asynchronous online education delivered via a pre-recorded video and face-to-face education) on HPV knowledge level and HPV vaccination intention among women aged 18-24 years.

The study will be conducted with women aged 18-24 years registered at Family Health Centers in the Afşin district of Kahramanmaraş, Türkiye. Eligible participants will be randomly assigned into three groups: the video-based education group, the face-to-face education group, and the control group.

Data will be collected using the Participant Information Form, HPV Knowledge Scale, and HPV Vaccination Attitude and Intention Form. Measurements will be performed at three time points: before the education (pre-test), immediately after the education (post-test), and one month after the education (follow-up test). The video-based education group will receive the education via a pre-recorded online video, while the face-to-face group will receive the same content in person at the Family Health Center. No education will be provided to the control group; only measurements will be obtained.

Research Questions

Does HPV education delivered through different methods increase HPV knowledge levels among young women?

Does HPV education increase HPV vaccination intention compared with the control group?

Is face-to-face education more effective than video-based education in increasing vaccination intention?

Are the improvements in knowledge and vaccination intention sustained one month after the education?

This study is a randomized controlled intervention designed to evaluate the effects of different educational methods on HPV and HPV vaccination knowledge level and vaccination intention among young women aged 18-24 living in the Afşin district of Kahramanmaraş, Türkiye. Participants will be randomly assigned into three groups: control group, video-based education group, and face-to-face education group.

At the beginning of the study, a pre-test will be administered to determine participants' baseline HPV and HPV vaccine knowledge and vaccination intention. Educational interventions prepared in accordance with national health guidelines will be delivered to the intervention groups, while no training will be provided to the control group. Immediately after the education sessions, a post-test will be applied to assess short-term effects, and a follow-up assessment one month later will evaluate the persistence of the effect.

Data will be collected at three time points using an introductory information form, the HPV Knowledge Scale, and the HPV Vaccination Attitude and Intention Form. The findings will be used to compare the effectiveness of different educational methods on HPV knowledge level and vaccination intention.

Inclusion Criteria:

Participants must meet all of the following criteria to be included in the study:

Aged 18-24 years,

Residing in Afşin district, Kahramanmaraş province,

Willing to voluntarily participate in the study,

Literate and able to understand survey questions in Turkish,

Have not previously received the HPV vaccine,

Agree to be available throughout the study period (pre-test, post-education test, and 1-month follow-up test),

Young women without physical or cognitive impairments or serious health problems that would prevent participation in the study.

Exclusion Criteria:

Participants will be excluded if they meet any of the following conditions:

Under 18 or over 24 years of age,

Have received the HPV vaccine or started the vaccine series,

Have been diagnosed with HPV infection,

Unable to attend the educational sessions or complete all stages of data collection (pre-test, post-education test, 1-month follow-up test),

Illiterate or unable to understand the study forms in Turkish,

Withdraw from the study or indicate unwillingness to continue participation,

Have serious hearing, vision, or cognitive impairments that would prevent meaningful engagement in the educational sessions.

Only individuals who are biologically female, identify as female, and are aged 18-24 years are eligible to participate in the study.

Individual participant data will not be shared because the dataset contains sensitive personal information related to participants' health, vaccination intention, and demographic details. To protect participant confidentiality and privacy, access to the data is restricted to the research team.

Masking was not possible due to the nature of the intervention; this is an open-label study.