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This prospective study aims to evaluate the effects of adenoidectomy and adenotonsillectomy on voice and speech functions in children. Changes in voice quality and resonance may occur after the removal of adenoid and tonsillar tissues, particularly in pediatric patients with enlarged adenoids or tonsils.
Objective voice assessments, including acoustic, aerodynamic, and nasalance measurements, as well as subjective voice-related quality of life questionnaires, will be performed before surgery and at the first and third months after surgery. The results of this study are expected to help clinicians better inform families about possible voice changes following adenoidectomy and adenotonsillectomy procedures.
This is a prospective, single-center observational study designed to evaluate the effects of adenoidectomy and adenotonsillectomy on voice and speech functions in pediatric patients.
A minimum of 36 children aged between 4 and 13 years who are scheduled for primary adenoidectomy or adenotonsillectomy will be included in the study. Written informed consent will be obtained from the parents or legal guardians of all participants prior to enrollment. All patients will undergo routine otolaryngological examination.
Voice recordings will be obtained in a sound-isolated room one day before surgery and at the first and third postoperative months. Recordings will be performed using an AKG P5-S dynamic microphone (AKG®, Vienna, Austria) and a Behringer UMC22 audio interface (Behringer®, Willich, Germany). The microphone will be positioned at approximately a 90-degree angle and 10 cm from the mouth while the patient is seated.
Participants will be instructed to sustain the vowel /a/ at a comfortable pitch and loudness following deep inspiration, repeated three times. The longest sustained phonation will be recorded as the maximum phonation time and used as an aerodynamic parameter.
Acoustic analysis will be performed using Praat software (Version 6.1.39; Paul Boersma and David Weenink, University of Amsterdam). Sustained vowel samples of 3-5 seconds will be analyzed to obtain fundamental frequency (F0), jitter, shimmer, and harmonics-to-noise ratio (HNR) values.
Nasalance measurements will be conducted using a Plex device and a dynamic microphone to evaluate nasal resonance and determine whether resonance values fall within normal limits.
All voice recordings will be captured using Audacity software and analyzed using Praat. Subjective voice assessment will be performed using the Pediatric Voice Handicap Index and the Pediatric Voice-Related Quality of Life questionnaires, both of which have been validated in Turkish. These questionnaires will be administered preoperatively and at the first and third postoperative months.
The study aims to provide objective and subjective data regarding voice changes following adenoidectomy and adenotonsillectomy and to support preoperative counseling of families regarding potential postoperative voice outcomes.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Children Undergoing Adenoidectomy or Adenotonsillectomy | Children aged 4-13 years scheduled for routine adenoidectomy or adenotonsillectomy. Participants are followed prospectively to evaluate changes in voice and speech parameters before surgery and at postoperative 1st and 3rd months. |
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| Measure | Description | Time Frame |
|---|---|---|
| Change in Fundamental Frequency (F0) | Fundamental frequency (F0), expressed in Hertz (Hz), will be measured using objective acoustic voice analysis with Praat software. Measurements will be obtained from sustained vowel /a/ recordings and compared between preoperative and postoperative evaluations. | Preoperative, 1 month postoperative, and 3 months postoperative |
| Change in Jitter Percentage | Jitter, expressed as a percentage (%), will be measured from sustained vowel /a/ recordings using Praat software. Preoperative jitter values will be compared with postoperative measurements at the 1st and 3rd months to assess changes in frequency stability after surgery. | Preoperative, 1 month postoperative, and 3 months postoperative |
| Change in Shimmer Percentage | Shimmer, expressed as a percentage (%), will be measured from sustained vowel /a/ recordings using Praat software. Measurements obtained preoperatively will be compared with postoperative values at the 1st and 3rd months to evaluate changes in amplitude stability following surgery. | Preoperative, 1 month postoperative, and 3 months postoperative |
| Change in Harmonics-to-Noise Ratio (HNR) | Harmonics-to-noise ratio (HNR), measured in decibels (dB), will be obtained from sustained vowel /a/ recordings using Praat software. Preoperative and postoperative (1st and 3rd months) values will be compared to assess changes in voice signal quality after surgery. | Preoperative, 1 month postoperative, and 3 months postoperative |
| Measure | Description | Time Frame |
|---|---|---|
| Change in Nasalance Scores After Surgery | Nasalance will be measured using a nasalance measurement system with a plex device and dynamic microphone. Nasalance scores are expressed as percentages ranging from 0% to 100%, with higher scores indicating increased nasal resonance. Preoperative and postoperative measurements will be compared. | Preoperative, 1 month postoperative, and 3 months postoperative |
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Inclusion Criteria:
Exclusion Criteria:
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This study includes children aged 4-13 years who are scheduled for primary adenoidectomy or adenotonsillectomy. The aim is to evaluate the effects of these surgical procedures on voice and speech function, using both objective acoustic measurements and validated pediatric voice-related quality of life questionnaires.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| DERYA CEBECİ, MD | Contact | +90 536 243 20 20 | drderyacebeci@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| DERYA CEBECİ, MD | Gaziosmanpaşa Training and Research Hospital, Department of Otolaryngology | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Gaziosmanpaşa Training and Research Hospital | Istanbul | 34245 | Turkey (Türkiye) |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 23834133 | Background | Kara M, Ozturk K, Ozer B. An evaluation of the effects of adenoidectomy on voice and speech function in children. Kulak Burun Bogaz Ihtis Derg. 2013 Jul-Aug;23(4):225-31. doi: 10.5606/kbbihtisas.2013.09476. | |
| Background | Adenotonsillektominin Akustik, Algısal ve Aerodinamik Ses Parametrelerine Etkisi. Beyhan Yılmaz, Engin Sengul, Musa Özbay, Salih Bakır. Dicle Tıp Dergisi /Dicle Medical Journal 2016; 43 (2): 333-338. doi: 10.5798/diclemedj.0921.2016.02.0691 | ||
| 31742023 |
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Individual participant data (IPD) from this study will not be shared outside of the research team due to the sensitive nature of pediatric patient data and privacy considerations.
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| Change in Pediatric Voice Handicap Index Scores | Subjective voice outcomes will be assessed using the Pediatric Voice Handicap Index (PVHI). The total score ranges from 0 to 92, with higher scores indicating greater perceived voice-related handicap. The validated Turkish version of the questionnaire will be administered preoperatively and postoperatively. | Preoperative, 1 month postoperative, and 3 months postoperative |
| Change in Pediatric Voice-Related Quality of Life Scores | Voice-related quality of life will be evaluated using the Pediatric Voice-Related Quality of Life (PVRQOL) questionnaire. Scores range from 0 to 100, with higher scores indicating better voice-related quality of life. The validated Turkish version will be used. | Preoperative, 1 month postoperative, and 3 months postoperative |
| Background |
| Inja RR, Paul RR, Varghese L, Santosh S, Sebastian T, Mathews SS. Voice Change Following Adenotonsillectomy in Pediatric Population: Myth or Reality?-A Pilot Study. Indian J Otolaryngol Head Neck Surg. 2019 Oct;71(Suppl 1):574-579. doi: 10.1007/s12070-018-1412-6. Epub 2018 Jun 4. |