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ClinicalTrials.gov ID

NCT07385976

Lead Sponsor

Far Eastern Memorial HospitalOTHER

Overall Status

Not yet recruiting

Study Type

Observational

Enrollment

100Estimated

Last Update Posted

Feb 4, 2026Actual

Start Date

Jan 19, 2026Estimated

Primary Completion Date

Dec 31, 2030Estimated

Completion Date

Dec 31, 2030Estimated

Official Title

The Role of Blood Perfusion in Cervical Cancer, Cervical Intraepithelial Neoplasm and Ovarian Cancer Patients

Brief Summary

This study will elucidate the role of 3D transvaginal ultrasound in assessing (1) cervical vascularity and blood flow in patients with cervical cancer and cervical intraepithelial neoplasm, and (2) tumor vascularity and blood flow in patients with ovarian cancer.

Detailed Description

Patients and methods:

Women with cervical cancer, cervical intraepithelial neoplasm, ovarian cancer, or the control will be invited to particilate in this study.Then, 3D power Doppler Ultrasound will be performed to capture (1) the cervical volume, vascularity and blood perfusion, and (2) ovarian tumor vascularity and blood perfusion. The sonographic data will be correlated to clinical and pathological data.

• Cervical Cancer
• Cervical Intraepithelial Neoplasm
• Ovarian Cancer

• Doppler ultrasound

Ages Eligible for Study

Child (0-17)Adult (18-64)Older Adult (65+)

Sexes Eligible for Study

Female

Accepts Healthy Volunteers

Yes

Eligibility Criteria

Inclusion Criteria:

• Regarding the topic "Hemoperfusion characteristics of cervical cancer and precancerous lesions, and the correlation between hemoperfusion and prognosis":

  1. Adult women who have had a normal cervical smear within the past three years and have no other gynecological cancers (control group).
  2. Adult women with cervical cancer or precancerous lesions.

• Regarding the topic "Correlation between hemoperfusion and prognosis of ovarian cancer":

  1. Adult women suspected of having ovarian cancer, fallopian tube cancer, or peritoneal cancer before surgery.

Exclusion Criteria:

• Regarding the topic "Hemoperfusion characteristics of cervical cancer and precancerous lesions of the cervix, and the correlation between hemoperfusion and prognosis":

  1. Patients who cannot cooperate with vaginal 3D ultrasound scans.

• Regarding the topic "Correlation between hemoperfusion and prognosis of ovarian cancer":

  1. Patients who cannot cooperate with vaginal or abdominal 3D ultrasound scans.

Observational Model

Case-Control

Time Perspective

Prospective

Lead Sponsor

Far Eastern Memorial HospitalOTHER

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