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The goal of this clinical trial is to learn if a longer period of lying on the back after corneal transplant surgery (Descemet Membrane Endothelial Keratoplasty, DMEK) helps the transplant stick better in the eye. It will also learn about side effects, such as back pain.
The main questions it aims to answer are:
Researchers will compare two groups:
Participants will:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 1 day supine positioning | Experimental |
| |
| 5 day supine positioning | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Duration of Supine Positioning | Procedure | 1 day supine positioning vs 5 days supine positioning |
|
| Measure | Description | Time Frame |
|---|---|---|
| Area of Graft Detachment in mm² | The area of graft detachment will be measured in mm² using anterior segment optical coherence tomography and a custom-built segmentation tool | First two postoperative weeks |
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Inclusion Criteria:
Fuchs Endothelial Corneal Dystrophy Bullous Keratopathy
Exclusion Criteria:
Comorbidities preventing supine positioning
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Maximilian Friedrich, MD | Contact | +49 6221 56 37749 | maximilian.friedrich@med.uni-heidelberg.de |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Ophthalmology, University Hospital Heidelberg | Recruiting | Heidelberg | 69120 | Germany |
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| ID | Term |
|---|---|
| D005642 | Fuchs' Endothelial Dystrophy |
| ID | Term |
|---|---|
| D003317 | Corneal Dystrophies, Hereditary |
| D003316 | Corneal Diseases |
| D005128 | Eye Diseases |
| D015785 | Eye Diseases, Hereditary |
| D030342 | Genetic Diseases, Inborn |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
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