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| ID | Type | Description | Link |
|---|---|---|---|
| 75651517.4.0000.5347 | Other Identifier | Universidade Federal do Rio Grande do Sul |
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The present study aimed to investigate the effects of cryotherapy on postoperative parameters (pain intensity, edema, trismus, and the quality of life) after lower third molar extraction. Patients underwent bilateral extraction of mandibular third molars in a single surgical procedure. Cryotherapy was applied to one side using facial ice packs, while no cryotherapy was performed on the contralateral side. Surgical procedures, postoperative instructions, and prescribed medications were identical for both sides. Consequently, the side treated with ice packs exhibited lower pain intensity, shorter pain duration, and reduced use of rescue medication.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group A | No Intervention | Patients in whom postoperative cryotherapy was not applied | |
| Group B | Experimental | Patients in whom postoperative cryotherapy was applied |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Cold Therapy | Other | Postoperative cold therapy applied with ice packs |
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| Measure | Description | Time Frame |
|---|---|---|
| Effects of cryotherapy on postoperative pain intensity after lower third molar extraction - using a visual analog scale. | Evaluate the effects of cryotherapy on postoperative pain intensity following lower third molar extraction using a visual analog scale (VAS) ranging from 0 to 10, where 0 indicates no pain and 10 represents the worst pain imaginable. Pain intensity was recorded daily by the participants over a 7-day postoperative period. | 7 days |
| Evaluate the effects of cryotherapy on postoperative edema after lower third molar extraction - using the mean of three linear facial measurements | Evaluate the effects of cryotherapy on postoperative edema following lower third molar extraction using three linear facial measurements: tragus to pogonion, tragus to oral commissure, and lateral canthus to the mandibular angle. Measurements were recorded in millimeters, and the mean of the three values was calculated to quantify edema. Assessments were performed preoperatively and postoperatively on the second and seventh days. | 7 days |
| Evaluate the effects of cryotherapy on postoperative trismus after lower third molar extraction - measuring maximum mouth opening | Evaluate the effects of cryotherapy on postoperative trismus following lower third molar extraction by measuring maximum mouth opening. Patients were seated with the tragus-ala plane parallel to the ground. Measurements were obtained using a measuring tape and recorded in millimeters. Assessments were performed on postoperative days 0, 2, and 7. | 7 days |
| Evaluate the effects of cryotherapy on postoperative quality of life after lower third molar extraction - using a questionnaire adapted from the Oral Health Impact Profile-14 (OHIP-14) | Evaluate the effects of cryotherapy on postoperative quality of life following lower third molar extraction using a questionnaire adapted from the Oral Health Impact Profile-14 (OHIP-14), consisting of 14 dichotomous (yes/no) questions addressing daily functional limitations. The questionnaire was administered on the day of surgery and completed by participants on postoperative days 0, 2, and 7. |
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Inclusion Criteria
Exclusion Criteria
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| Type | Includes Protocol | Includes SAP | Includes ICF | Document Label | Document Date | Document Uploaded Date | Document File Name |
|---|---|---|---|---|---|---|---|
| Prot_SAP_ICF | Yes | Yes | Yes | Study Protocol, Statistical Analysis Plan, and Informed Consent Form | Dec 30, 2025 | Jan 2, 2026 | Prot_SAP_ICF_000.pdf |
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| ID | Term |
|---|---|
| D017679 | Cryotherapy |
| ID | Term |
|---|---|
| D013812 | Therapeutics |
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Randomized split-mouth clinical trial
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| 7 days |