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This study is going to asses and compare the efficacy of treatment of macular amyloidosis using microneedling vs PRP with microneedling. Pruritus and pigmentation will be assessed.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| microneedling | Active Comparator | microneedling will be done on the first arm |
|
| macular amyloidosis treated with microneedling and PRP | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| microneedling | Device | microneedling will be done for the one arm of macular amyloidosis |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Improvement of macular amyloidosis using microneedling or PRP with microneedling |
1< 25% improvement 2=25-<50% improvement 3=50-<75% improvement 4> 75% improvement 3. Degree of improvement in dermoscopic features will be measured by scoring system as follows : 0-25% = 0 (no improvement) 26-50% = 1(mild improvement) 51-75% = 2 (moderate improvement) 76- 100% = 3 (marked improvement) 4. Patients' satisfaction: Visual Analog Score for pain 5.measuring the Treatment Satisfaction Questionnaire for Medication (TSQM) for effectiveness. 6. TPhysician global satisfaction will be assessed. 0-3 (unsatisfied) 4-6 (satisfied) 7-10 (highly satisfied) | 3 months |
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Inclusion Criteria: • Both genders were included.
Exclusion Criteria: • Prior use of topical therapies in the previous 4 weeks.
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Amira Elbendary, MD | Contact | +201552208664 | aelbendary@kasralainy.edu.eg |
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| ID | Term |
|---|---|
| D000097244 | Percutaneous Collagen Induction |
| ID | Term |
|---|---|
| D000529 | Complementary Therapies |
| D013812 | Therapeutics |
| D026741 | Physical Therapy Modalities |
| D011677 | Punctures |
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Face split
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| microneedling with PRP |
| Device |
microneedling with PRP will be done on macular amyloidosis |
|
| D012046 |
| Rehabilitation |