Microneedling Alone vs Microneedling With PRP in the Treatment of Macular Amyloidosis; a Split Face Comparative Study

Comparison Between Efficacy and Safety of PRP With Microneedling and Microneedling Alone in Treatment of Macular Amyloidosis; a Split Face Blinded Non Randomized Control Trial With Dermoscopic and Histopathologic Evaluation

This study is going to asses and compare the efficacy of treatment of macular amyloidosis using microneedling vs PRP with microneedling. Pruritus and pigmentation will be assessed.

Inclusion Criteria: • Both genders were included.

• Patients above 18 years old.
• Patients diagnosed by macular amyloidosis, proved by dermoscopy and histopathology.

Exclusion Criteria: • Prior use of topical therapies in the previous 4 weeks.

• Prior use of any procedures such as chemical peel or laser treatment in the previous 1 month.
• Prior use of any systemic treatment for macular amyloidosis in the past 12 weeks.
• Patients with other skin conditions (e.g., psoriasis, eczema).
• Immunocompromised patients (HIV, chemotherapy).
• Patients with history of any type of autoimmune disorders, coagulopathies, and keloid tendency.
• Known or suspected allergy to ingredients