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Microneedling with topical INSULIN is a simple, effective tool for building body's new collagen layers and thus an alternative to all erosive techniques such as lasers, peels. The skin responds to fine punctures with the release of growth factors. 8 It is a safe procedure that can be performed in the office without complications, with a good cost-benefit because it is economically viable without any effect on patient's daily activities. 9
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| GROUP A Microneedling with PRP(platelete rich plasma) | Experimental |
| |
| GROUP B Microneedling with topical INSULIN | Experimental |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| PRP( platelet rich plasma) and Insulin human | Drug | Microneedling with autologus PRP reduces inflammationin acne scars. Insulin human is a new topical drug which is used nowadays for acne scars as it is more effective in producing collagen formation as well as new blood vessel formation |
| Measure | Description | Time Frame |
|---|---|---|
| Efficacy of Topical Insulin R with microneedling versus Platelets rich plasma in atrophic acne scars | Efficacy will be assessed by using Goodman and Baron Qualitative Scar Grading System | Efficacy will be assesed upto 4 months. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| KHADIJA ASADULLAH, MBBS | JPMC | Principal Investigator |
| FAIZA INAM, FCPS | JPMC | Principal Investigator |
| PARISA SANAWAR, FCPS | JPMC | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| JPMC | Karachi | Sindh | Pakistan |
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