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Coronary artery bypass grafting (CABG) is a major cardiac surgery associated with risks of serious perioperative complications and mortality. Malnutrition and inflammation are known independent risk factors for poor outcomes in patients with coronary artery disease. This retrospective observational study evaluates the Prognostic Nutritional Index (PNI)-a simple score derived from serum albumin and lymphocyte counts-as an objective measure of nutritional and inflammatory status. The research aims to determine how well preoperative PNI and its postoperative changes can predict complications such as acute kidney injury, myocardial infarction, and sternal wound infections in patients undergoing CABG.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| CABG Patient Cohort. | Patients who underwent Coronary Artery Bypass Grafting surgery at Benha University Hospital over the preceding five years. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Prognostic Nutritional Index (PNI) | Diagnostic Test | Calculated using serum albumin (g/L) and total peripheral lymphocyte count. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Diagnostic Accuracy of the Prognostic Nutritional Index (PNI) in Predicting Post-CABG Complications. | The Area Under the Receiver Operating Characteristic (ROC) Curve (AUC) used to determine the performance of the PNI score in predicting the occurrence of major postoperative complications. | Approximately 30 days (From surgery through the duration of the hospital/ICU stay.) |
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Inclusion Criteria:
Exclusion Criteria:
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The study population consists of adult patients (both male and female) who underwent major coronary artery bypass grafting surgery at the Cardiothoracic Surgery Department of Benha University Hospital within a recent five-year period.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Benha University | Banhā | Al Qalyoubia | 13511 | Egypt |
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| Neutrophil-to-Lymphocyte Ratio (NLR) | Diagnostic Test | Calculated from peripheral blood counts. |
|
| Body Mass Index (BMI) | Diagnostic Test | Calculated from preoperative weight and height. |
|
| ID | Term |
|---|---|
| D003324 | Coronary Artery Disease |
| ID | Term |
|---|---|
| D003327 | Coronary Disease |
| D017202 | Myocardial Ischemia |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D001161 | Arteriosclerosis |
| D001157 | Arterial Occlusive Diseases |
| D014652 | Vascular Diseases |
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| ID | Term |
|---|---|
| D015992 | Body Mass Index |
| ID | Term |
|---|---|
| D001837 | Body Weights and Measures |
| D001824 | Body Constitution |
| D010808 | Physical Examination |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
| D000886 | Anthropometry |
| D008919 | Investigative Techniques |
| D010829 | Physiological Phenomena |
| D001699 | Biometry |
| D015991 | Epidemiologic Measurements |
| D011634 | Public Health |
| D004778 | Environment and Public Health |
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