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| Name | Class |
|---|---|
| The Leona M. and Harry B. Helmsley Charitable Trust | OTHER |
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The goal of this clinical trial is to use a modified thermal probe to measure temperature rise in the colonic mucosa of participants with inflammatory bowel disease, Crohn's disease, and/or ulcerative colitis. The main question it aims to answer is:
Is the thermal probe an effective device to use to detect temperature rise in the colonic mucosa?
During the participant's standard of care colonoscopy, the thermal probe will be inserted into the colonoscope. The thermal probe is connected to a temperature transmitter that collects and saves the temperature of the colon in real time.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| IBD, Crohn's Disease, and/or UC | Experimental | 10 adult participants currently diagnosed with inflammatory bowel disease (IBD), Crohn's disease, and/or ulcerative colitis (UC) will be enrolled at MGH |
|
| Undergoing Colorectal Screening | Experimental | 10 adult subjects undergoing colorectal cancer screening will be enrolled at MGH |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Feasibility of using a thermal probe to measure temperature rise in colonic mucosa | Device | 10 participants in each arm will be enrolled in this study. All consented participants will receive the same intervention. |
| Measure | Description | Time Frame |
|---|---|---|
| Ability of thermal probe to collect temperature measurements from colonic mucosa | Thermal measurements are collected during the study procedure and analyzed within one year of collection. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Guillermo Tearney, M.D., PhD | Massachusetts General Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | United States |
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| ID | Term |
|---|---|
| D015212 | Inflammatory Bowel Diseases |
| D003424 | Crohn Disease |
| D003093 | Colitis, Ulcerative |
| ID | Term |
|---|---|
| D005759 | Gastroenteritis |
| D005767 | Gastrointestinal Diseases |
| D004066 | Digestive System Diseases |
| D007410 | Intestinal Diseases |
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All study participants will get the same intervention
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| D003092 | Colitis |
| D003108 | Colonic Diseases |