Imaging the Colon Using a Colonoscope Compatible Imaging Probe

Study for Imaging the Lower Gastrointestinal Tract Using a Colonoscopy-Compatible OCT Probe

The goal of this study is to use a colonoscope compatible device capable of taking images of the lower gastrointestinal tract. The main question it aims to answer is:

Is the colonoscope compatible optical coherence tomography probe (CC-OCT probe) an effective device to use to take images of the gut?

During the participant's standard of care colonoscopy, the CC-OCT probe will be inserted into the colonoscope. The CC-OCT probe will then collect images of the participant's gastrointestinal tract in real time.

Inclusion Criteria:

• 45 years of age or older
• Capable of giving informed consent
• Capable of following bowel prep instructions

Exclusion Criteria:

• 75 years of age or older
• Any contraindication to bowel prep or colonoscopy
• Current diagnosis of any bleeding disorders
• Currently using drugs that interfere with coagulation (excluding low-dose aspirin)
• Pregnancy