A Phase III, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Evaluate the Efficacy and Safety of Once-Weekly RO7795068 Administered to Participants With Obesity or Overweight Without Type 2 Diabetes
A Phase III, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Evaluate the Efficacy and Safety of Once-Weekly RO7795068 Administered to Participants With Obesity or Overweight Without Type 2 Diabetes
The purpose of this study is to assess the efficacy and safety of enicepatide, a dual glucagon like peptide-1 (GLP-1)/glucose-dependent insulinotropic polypeptide (GIP) receptor agonist (RA), at multiple doses compared with placebo for weight management in participants without Type 2 diabetes mellitus (T2DM) who have obesity or overweight with at least one weight-related comorbidity.
Inclusion Criteria:
Participants must have at screening:
History of ≥1 self-reported unsuccessful diet/exercise effort to lose body weight
Ability and willingness to self-administer the study drug (or receive an injection from a trained individual if visually impaired or with physical limitations)
Exclusion Criteria:
global-roche-genentech-trials@gene.com888-662-6728 (U.S. Only)
West Chester, Pennsylvania 19380, United States
Dallas, Texas 75390, United States
Southlake, Texas 76092, United States
Salt Lake City, Utah 841480001, United States
Ciudad Autonoma Buenos Aires, C1204AAD, Argentina
Ciudad Autonoma Buenos Aires, C1425AGC, Argentina
Oaklands Park, South Australia 5046, Australia
Goiânia, Goiás 74605-020, Brazil
Porto Alegre, Rio Grande do Sul 90430-001, Brazil
São José do Rio Preto, São Paulo 15090-000, Brazil
Luoyang, DUMMY_VALUE, China
Plze?, 301 00, Czechia
Paris, 75015, France
Paris, 75671, France
Bad Oeynhausen, 32545, Germany
Erlangen, 91054, Germany
Hof, 95030, Germany
Köln - Dünnwald, 51069, Germany
Münster, 48153, Germany
Debrecen, 4032, Hungary
Szeged, 6725, Hungary
Székesfehérvár, 8000, Hungary
Bergamo, Abruzzo 24127, Italy
Catanzaro, Calabria 88100, Italy
Bologna, Emilia-Romagna 40138, Italy
Hokkaido, 060-0061, Japan
Hokkaido, 066-0032, Japan
Col Saucito, Chihuahua 31110, Mexico
Guadalajara, Jalisco 44650, Mexico
Delegacion Cuauhtemoc, Mexico CITY (federal District) 06100, Mexico
México, Mexico CITY (federal District) 14000, Mexico
Cuernavaca, Morelos 62250, Mexico
Ciudad Madero, Tamaulipas 89440, Mexico
Bydgoszcz, 85-231, Poland
Tychy, 43-100, Poland
Zamo??, 22-400, Poland