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| Name | Class |
|---|---|
| Corxel Pharmaceuticals | INDUSTRY |
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This study is to evaluate the food effect (FE) on the PK of 200 mg CX11 in healthy participants
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Fasted-Fed Arm | Experimental | Fasted-Fed Group |
|
| Fed-Fasted Arm | Experimental | Fed-Fasted Group |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| CX11 (VCT220) | Drug | CX11 (VCT220) administered orally to participants who are in fasted/fed state in the first 6 consecutive days, and in fed/fasted state on the 7th day |
|
| Measure | Description | Time Frame |
|---|---|---|
| Area Under the Concentration-time curve from 0 to 24 hour (AUC0-24) of CX11 (VCT220) | AUC0-24 of of CX11 (VCT220) | Predose at Day1 up to 35 days postdose |
| Maximum Observed Concentration (Cmax) of CX11 (VCT220) | Cmax of CX11 (VCT220) | Predose at Day1 up to 35 days postdose |
| Time to Maximum Observed Concentration (Tmax) of CX11 (VCT220) | Tmax of CX11 (VCT220) | Predose at Day 1 up to 35 days postdose |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Wang | Contact | +86-13918150895 | Yinghua.wang@corxelbio.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Shanghai Xuhui Central Hospital | Recruiting | Shanghai | Shanghai Municipality | China |
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| ID | Term |
|---|---|
| D009765 | Obesity |
| D050177 | Overweight |
| D003924 | Diabetes Mellitus, Type 2 |
| ID | Term |
|---|---|
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
| D001835 | Body Weight |
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| D012816 |
| Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D003920 | Diabetes Mellitus |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D004700 | Endocrine System Diseases |