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The purpose of this study is to investigate the effect of food on the time course of PH-797804 concentration in the blood following dosing by oral immediate release tablet formulation.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| PH-797804 1 mg Fasted | Experimental | Subjects will receive a single 1 mg dose in the fasted state |
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| PH-797804 1 mg Fed | Experimental | Subjects will receive a single 1 mg dose following a high-fat meal |
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| PH-797804 10 mg Fasted | Experimental | Subjects will receive a single 10 mg dose in the fasted state |
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| PH-797804 10 mg Fed | Experimental | Subjects will receive a single 10 mg dose following a high-fat meal |
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| PH-797804 24 mg Fed | Experimental | Subjects will receive a single 24 mg dose following a high-fat meal |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| PH-797804 | Drug | Tablet, 1 mg, single dose |
| |
| PH-797804 |
| Measure | Description | Time Frame |
|---|---|---|
| Pharmacokinetics: peak plasma concentration | 0,1,2,3,4,6,8,12,24,48,72,96,144,192,264,312 hours post-dose | |
| Pharmacokinetics: time to peak plasma concentration | 0,1,2,3,4,6,8,12,24,48,72,96,144,192,264,312 hours post-dose | |
| Pharmacokinetics: area under the plasma concentration-time curve | 0,1,2,3,4,6,8,12,24,48,72,96,144,192,264,312 hours post-dose | |
| Pharmacokinetics: terminal plasma half-life | 0,1,2,3,4,6,8,12,24,48,72,96,144,192,264,312 hours post-dose |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Pfizer CT.gov Call Center | Pfizer | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Pfizer Investigational Site | Singapore | 188770 | Singapore |
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| Label | URL |
|---|---|
| To obtain contact information for a study center near you, click here. | View source |
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| ID | Term |
|---|---|
| C542398 | PH 797804 |
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| Drug |
Tablet, 1 mg, single dose |
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| PH-797804 | Drug | Tablet, 10 mg, single dose |
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| PH-797804 | Drug | Tablet, 10 mg, single dose |
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| PH-797804 | Drug | Tablet, 24 mg, single dose |
|