Effect of Patellar Denervation on Post-operative Knee Pai... | NCT07342166

Studies
Effect of Patellar Denervation on Post-operative Knee Pain and Knee Function in Total Knee Arthroplasty

NCT07342166

Sponsor

Queen Savang Vadhana Memorial Hospital, Thailand

Status

Completed

Last Update Posted

Jan 15, 2026Actual

Enrollment

64Actual

Phase

Not Applicable

Conditions

Osteoarthritis, Knee

Interventions

Patellar Denervation

Countries

Thailand

Protocol Section

Identification Module Status Module Sponsor/Collaborators Module Oversight Module Description Module Conditions Module Design Module Arms/Interventions Module Outcomes Module Eligibility Module Contacts/Locations Module References Module IPD Sharing Statement Module

Results Section

Participant Flow Module Baseline Characteristics Module Outcome Measures Module Adverse Events Module More Info Module

Annotation Section

Annotation Module

Document Section

Large Document Module

Derived Section

Miscellaneous Info Module Condition Browse Module Intervention Browse Module

Protocol Section

Identification Module

NCT ID

Results Section

No data available

No data is available for this block.

Annotation Section

No data available

No data is available for this block.

Document Section

No data available

No data is available for this block.

Derived Section

Miscellaneous Info Module

Version Holder

Status Module

Record Verification Date

Jan 2026

Overall Recruitment Status or Expanded Access Status

Completed

Last Known Status

Not provided

Delayed Posting

Not provided

Why Stopped

Not provided

Expanded Access Info

Start Date

Aug 8, 2023Actual

Primary Completion Date

Jun 21, 2025Actual

Completion Date

Jun 21, 2025Actual

First Submitted Date

Dec 25, 2025

First Submission Date that Met QC Criteria

Jan 7, 2026

First Posted Date

Jan 15, 2026Actual

Results Waived

Not provided

Results First Submitted Date

Not provided

Results First Submitted that Met QC Criteria

Not provided

Results First Posted Date

Not provided

Certification/Extension (aka Delayed Results) First Submitted Date

Not provided

Certification/Extension First Submitted that Passed QC Review

Not provided

Certification/Extension First Posted Date

Not provided

Last Update Submitted Date

Jan 7, 2026

Last Update Posted Date

Jan 15, 2026Actual

Oversight Module

Has Data Monitoring Committee (DMC)

Yes

Is FDA Regulated Drug

Is FDA Regulated Device

Is Unapproved Device

Not provided

Pediatric Postmarket Surveillance of a Device Product

Not provided

Product Exported from US

Not provided

FDAAA801 Violation

Not provided

Description Module

Brief Summary

This study is a double-blind randomized controlled trial aiming to investigate the effects of patellar denervation using electrocautery on postoperative knee pain and knee function in patients undergoing primary total knee arthroplasty (TKA) without patellar resurfacing.

Detailed Description

This study is a prospective, double-blind randomized controlled trial conducted at Queen Savang Vadhana Memorial Hospital between 2023 and 2025. The aim of the study is to assess the effect of patellar denervation using electrocautery on postoperative knee pain and knee function in patients undergoing primary total knee arthroplasty (TKA) without patellar resurfacing.

Sixty-four patients were enrolled and randomly assigned to either the patellar denervation group (PD) or the non-denervation group (NPD), with 32 participants in each group.

Design Module

Study Type

Interventional

Number of References to an Expanded Access Study

Not provided

Expanded Access Types

Not provided

Patient Registry

Not provided

Target Follow-Up Duration

Not provided

Phases

Not Applicable

Interventional Study Design

Allocation

Biospecimen

No data available

No data is available for this block.

Enrollment

64Actual

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
Patellar Denervation	Experimental		Procedure: Patellar Denervation
Non-Patellar Denervation	No Intervention

Interventions

Name	Type	Description	Arm Group Labels	Other Names
Patellar Denervation	Procedure	Electrocautery patella circumferentially during total knee arthroplasty	Patellar Denervation

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
Visual analog scale score for knee pain		2 weeks, 6 weeks, 3 months, 6 months, and 12 months

Secondary Outcomes

Measure	Description	Time Frame
Kujala score		3 months, 1 year
Knee Society score		3 months, 1 year
Timed up and go test

Other Outcomes

Not provided

Eligibility Module

Eligibility Criteria

Inclusion Criteria:

Age 55-85 years old
Knee osteoarthritis
Plan for total knee arthroplasty after failed conservative treatment for at least 3 months

Exclusion Criteria:

Previous history of trauma, fracture or open surgery on the same knee
Inflammatory arthritis or Crystal-induced arthritis
Patellar instability or isolated patellofemoral osteoarthritis
Unable to answer questionnaire
Cannot tolerate surgery due to medical comorbidities

Accepts Healthy Volunteers

Sex

All

Sex/Gender Based

Not provided

Sex/Gender Description

Not provided

Minimum Age

55 Years

Maximum Age

85 Years

Standard Ages

AdultOlder Adult

Study Population

Not provided

Sampling Method

Not provided

Contacts/Locations Module

Central Contacts

Not provided

Overall Officials

Not provided

Locations

Facility	Status	City	State	ZIP	Country	Contacts
Chalathorn Kulthonchalanan		Chon Buri	Changwat Chon Buri	20110	Thailand

IPD Sharing Statement Module

Plan to Share IPD

Description

Data was save in form of Google sheet

Types

Not provided

Time Frame

Not provided

Access Criteria

Not provided

URL

Not provided

Condition Browse Module

MeSH Terms

ID	Term
D020370	Osteoarthritis, Knee

Ancestor Terms

ID	Term
D010003	Osteoarthritis
D001168	Arthritis
D007592	Joint Diseases
D009140	Musculoskeletal Diseases

Browse Leaves

Not provided

Browse Branches

Not provided