Dental implants are considered a predictable rehabilitation option for tooth extraction or missing teeth. The use of dental implants has evolved into a viable prosthetic alternative to conventional tooth-supported fixed prostheses or removable dentures, with advantages in terms of patient satisfaction and quality of life. Long-term studies have reported excellent success and survival rates for implants used in prosthetic rehabilitation. Benefits in terms of patient satisfaction and preservation of adjacent tooth structure are among the advantages of implant-supported restorations over prosthetic alternatives. However, dental implants can be subject to mechanical and biological complications. After the first year of function, marginal bone loss is minimal around most oral implants. Nevertheless, marginal bone loss or the onset of bacterial-related biological complications, such as mucositis and peri-implantitis, can occur. Despite the growing number of publications in the field of implant rehabilitation, to date only a few studies have investigated the outcomes of implant rehabilitation in a hospital setting characterized by patients with concomitant or previous systemic therapies and pathologies. The objective of this study is to evaluate the success of implant therapy, peri-implant marginal bone resorption (MBL), clinical parameters of peri-implant health, aesthetic parameters of rehabilitation, and patient-reported treatment outcomes in a sample of patients treated in a hospital setting.

Inclusion Criteria:

• Patients requiring implant surgery for edentulous rehabilitation;
• Age > 18;
• Achievement of FMPS and FMBS ≤ 15%;
• Signed written informed consent to participate in the study.

Exclusion Criteria:

• Uncontrolled diabetes or hypertension;
• Uncontrolled periodontal disease;
• Inability to perform consistent and continuous follow-up;
• Pregnancy or breastfeeding;
• Inability to provide written informed consent.

Patients aged >18 years who require implant-supported rehabilitation